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Table 5 Comparison of MCCB subtest scores in patients with different genotypes of the rs2303579 locus

From: Association between polymorphism of the NEDD4 gene and cognitive dysfunction of schizophrenia patients in Chinese Han population

Subtest

rs2303579

F

P

P1

P2

P3

CC (n = 95)

TT (n = 67)

CT (n = 134)

TMT-A

48.02 ± 8.599

46.52 ± 18.220

46.09 ± 11.257

0.641

0.527

0.431

0.276

0.889

BACS: Symbol Coding

42.58 ± 10.389

42.82 ± 10.027

40.78 ± 10.012

1.408

0.246

0.850

0.172

0.157

Fluency

49.13 ± 9.905

47.75 ± 12.499

46.64 ± 11.583

1.414

0.245

0.467

0.094

0.470

CPT-IP

42.77 ± 10.616

42.58 ± 9.999

41.12 ± 11.657

0.845

0.431

0.947

0.243

0.333

LNS

46.91 ± 10.070

45.54 ± 10.140

45.22 ± 12.420

0.623

0.537

0.427

0.285

0.911

WMS-III: Spatial Span

45.83 ± 12.232

46.16 ± 11.764

42.46 ± 13.507

2.917

0.056

0.843

0.045*

0.046*

HVLT-R

44.20 ± 11.273

47.39 ± 10.113

43.28 ± 11.388

2.786

0.063

0.081

0.587

0.020*

BVMT-R

43.83 ± 11.793

44.22 ± 12.007

42.49 ± 11.764

0.614

0.542

0.832

0.369

0.328

NAB: Mazes

43.88 ± 9.947

43.93 ± 10.458

41.82 ± 10.115

1.195

0.304

0.946

0.167

0.247

MSCEIT: Managing Emotions

48.33 ± 11.862

48.12 ± 12.957

47.60 ± 11.574

0.078

0.925

0.883

0.695

0.846

  1. Notes: P1 value represented the statistical significance between patients with CC genotype and TT genotype. P2 value represented the statistical significance between patients with CC genotype and CT genotype. P3 value represented the statistical significance between patients with TT genotype and CT genotype. * P < 0.05