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Table 6 Comparison of MCCB subtest scores in patients with different genotypes of the rs62043855 locus

From: Association between polymorphism of the NEDD4 gene and cognitive dysfunction of schizophrenia patients in Chinese Han population

Subtest

rs62043855

F

P

P1

P2

P3

TT(n = 126)

GG(n = 39)

TG(n = 131)

TMT-A

47.30 ± 8.989

47.49 ± 18.530

46.13 ± 13.206

0.706

0.494

0.822

0.243

0.561

BACS: Symbol Coding

42.59 ± 10.301

43.26 ± 9.332

40.66 ± 10.181

2.211

0.111

0.952

0.053

0.161

Fluency

48.60 ± 10.777

47.54 ± 11.480

46.85 ± 11.766

1.014

0.364

0.516

0.158

0.748

CPT-IP

42.23 ± 11.058

42.49 ± 9.965

41.59 ± 11.215

0.400

0.671

0.862

0.379

0.665

LNS

46.83 ± 9.858

45.28 ± 10.105

45.03 ± 12.634

1.962

0.142

0.230

0.058

0.922

WMS-III: Spatial Span

45.20 ± 12.497

45.54 ± 12.553

43.25 ± 13.172

0.949

0.388

0.908

0.215

0.330

HVLT-R

44.41 ± 11.462

47.03 ± 10.786

43.85 ± 10.941

1.246

0.289

0.305

0.453

0.120

BVMT-R

44.14 ± 12.068

45.21 ± 11.225

41.95 ± 11.671

1.669

0.190

0.621

0.144

0.131

NAB: Mazes

43.61 ± 10.299

45.44 ± 9.210

41.60 ± 10.162

2.723

0.067

0.370

0.092

0.03*

MSCEIT: Managing Emotions

47.72 ± 11.473

48.26 ± 14.365

48.08 ± 11.717

0.013

0.987

0.880

0.909

0.942

  1. Notes: P1 value represented the statistical significance between patients with TT genotype and GG genotype. P2 value represented the statistical significance between patients with TT genotype and TG genotype. P3 value represented the statistical significance between patients with GG genotype and TG genotype. * P < 0.05