Anomalies in uncinate fasciculus development and social defects in preschoolers with autism spectrum disorder

BMC Psychiatry

Table 1 Participants: clinical demographics

	ASD group	DD group	t/x²	P
N	37	27
Gender (male: female)	31:5	22:5	0.297	0.586
⊿ in age (months)	24.44 ± 4.48	24.74 ± 6.03	−0.224	0.824
Time 1
Age (month)	30.86 ± 3.97	28.89 ± 5.23	1.701	0.094
DQ	69.19 ± 14.04	69.42 ± 17.42	−0.057	0.955
ADI-R
Social Deficits	21.06 ± 6.16	12.22 ± 8.67	4.731	0.000***
Abnormalities in Communication	12.31 ± 3.71	7.30 ± 5.78	4.184	0.000***
RRB	4.53 ± 2.56	1.96 ± 1.89	4.385	0.000***
CARS	36.28 ± 4.12	27.33 ± 6.37	6.757	0.000***
Time 2
Age (month)	55.31 ± 3.99	53.63 ± 4.09	1.632	0.108
IQ	85.56 ± 16.98	84.88 ± 25.61	0.114	0.910
ADI-R
Social Deficits	17.83 ± 6.27	14.07 ± 8.53	2.017	0.048*
Abnormalities in Communication	12.56 ± 4.45	8.15 ± 5.36	3.563	0.001**
RRB	4.47 ± 2.01	2.74 ± 2.14	3.293	0.002**
CARS	34.11 ± 3.80	28.00 ± 8.51	3.835	0.000***

ADI-R Autism Diagnostic Interview Scale (Revised Edition), BSID-CR Bailey Infant Development Scale (China Urban Revision), CARS Child Autism Rating Scale; ⊿ in age: the interval between two scans * P<0.05; **P<0.01

ISSN: 1471-244X