Sexual dimorphism in up-regulation of suppressors of cytokine signaling genes in patients with bipolar disorder

Table 3 Relative expression of SOCS genes in BD patients compared with controls

Genes	Parameters	Total patients vs. total controls (50 vs. 50)	Male patients vs. male controls (35 vs. 35)	Female patients vs. female controls (15 vs. 15)
SOCS1	Expression ratio	2.07	4.43	0.61
SOCS1	P-value	0.005	< 0.001	0.14
SOCS2	Expression ratio	3.85	8	1.21
SOCS2	P-value	< 0.001	< 0.001	0.47
SOCS3	Expression ratio	2.7	4.82	1.19
SOCS3	P-value	< 0.001	< 0.001	0.61
SOCS5	Expression ratio	5.77	8.77	3.81
SOCS5	P-value	< 0.001	< 0.001	0.001