Table 1 Clinical features of the GUIDED intent-to-treat study population at baseline (week 0)
| Â | Treatment | Â | |
|---|---|---|---|
Characteristic | TAU (N = 781) | Guided-Care (N = 760) | Total (N = 1541) |
HAM-D17 | |||
 Mean (SD) | 20.74 (4.86) | 20.49 (4.84) | 20.62 (4.85) |
 Min, Max | 6.0, 35.0 | 4.0, 37.0 | 4.0, 37.0 |
Depression Category, n (%) | |||
 None (0–7) | 5 (0.6) | 6 (0.8) | 11 (0.7) |
 Mild (8–13) | 46 (5.9) | 45 (5.9) | 91 (5.9) |
 Moderate (14–18) | 189 (24.2) | 209 (27.5) | 398 (25.8) |
 Severe (19–22) | 270 (34.6) | 241 (31.7) | 511 (33.2) |
 Very Severe (≥ 23) | 271 (34.7) | 259 (34.1) | 530 (34.4) |
HAM-D6 | |||
 Mean (SD) | 10.90 (2.16) | 10.99 (2.11) | 10.94 (2.13) |
 Min, Max | 1.0, 17.0 | 3.0, 18.0 | 1.0, 18.0 |
Failed Medication Trials | |||
 Mean (SD) | 3.54 (3.01) | 3.45 (3.02) | 3.49 (3.01) |
 Min, Max | 1, 34 | 1, 25 | 1, 34 |
Psychiatric Comorbidities, n (%) | |||
 General anxiety disorder | 104 (13.4) | 127 (16.7) | 231 (15.0) |
 Panic disorders/social phobia | 112 (14.4) | 119 (15.7) | 231 (15.0) |
 Post-traumatic stress disorder | 35 (4.5) | 41 (5.4) | 76 (4.9) |