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Table 3 Proportion of patients treated with each medication class out of those receiving first-line therapy (includes mono- or combination therapy)

From: Treatment patterns and sequences of pharmacotherapy for patients diagnosed with depression in the United States: 2014 through 2019

 

CCAE

(N = 80,810)

MDCD

(N = 33,186)

MDCR

(N = 3764)

Optum

(N = 51,585)

SSRI

46,432

57.5%

12,035

36.3%

1693

45.0%

25,942

50.3%

Anxiolytic

14,625

18.1%

6141

18.5%

695

18.5%

9095

17.6%

Other antidepressant

12,196

15.1%

3578

10.8%

518

13.8%

7438

14.4%

Hypnotic/Sedative

6981

8.6%

666

2.0%

99

2.6%

1218

2.4%

Anticonvulsant

7377

9.1%

1813

5.5%

514

13.7%

5855

11.4%

SNRI

4531

5.6%

966

2.9%

249

6.6%

3145

6.1%

Antipsychotic

4609

5.7%

2120

6.4%

275

7.3%

2944

5.7%

Tricyclic

1426

1.8%

842

2.5%

61

1.6%

926

1.8%

Stimulant

1048

1.3%

426

1.3%

19

0.5%

1537

3.0%

Lithium

246

0.3%

106

0.3%

2

0.1%

110

0.2%

MAOI

7

0.0%

2

0.0%

3

0.1%

16

0.0%

  1. Abbreviations: CCAE IBM MarketScan® Commercial Database, MDCD IBM MarketScan® Multi-State Medicaid Database, MDCR IBM MarketScan® Medicare Supplemental Database, SSRI Selective serotonin reuptake inhibitor, SNRI Serotonin and norepinephrine reuptake inhibitor, MAOI Monoamine oxidase inhibitor