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Table 5 Treatment patterns of those receiving first line monotherapy SSRI treatment

From: Treatment patterns and sequences of pharmacotherapy for patients diagnosed with depression in the United States: 2014 through 2019

 

CCAE

MDCD

MDCR

Optum

Received first line SSRI (monotherapy)

34,453

 

8292

 

1341

 

19,588

 

Patients on first line SSRI monotherapy who went on to receive second treatment class

19,231

55.8%

4812

58.0%

703

52.4%

10,090

51.5%

 Second line is combination therapy

7814

40.6%

1784

37.1%

265

37.7%

4034

40.0%

 Second line is combination therapy which includes an SSRI

6085

31.6%

1309

27.2%

224

31.9%

3200

31.7%

 Second line is combination therapy of SSRI + antipsychotic

828

4.3%

325

6.8%

31

4.4%

385

3.8%

  1. Abbreviations: CCAE IBM MarketScan® Commercial Database, MDCD IBM MarketScan® Multi-State Medicaid Database, MDCR IBM MarketScan® Medicare Supplemental Database, SSRI Selective serotonin reuptake inhibitor