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Table 3 Associations between CYP1A2, UGT1A4, and ABCB1 genotypes and autonomic nervous system activity

From: The association of genetic polymorphisms in CYP1A2, UGT1A4, and ABCB1 with autonomic nervous system dysfunction in schizophrenia patients treated with olanzapine

CYP1A2
 rs2069514rs762551
G/GG/A, A/APC/CC/A, A/AP
5635 2170 
lnLF (ms2)4.40 ± 1.124.17 ± 1.110.3374.84 ± 0.844.16 ± 1.150.013
lnHF (ms2)3.86 ± 1.223.72 ± 1.050.5974.15 ± 1.453.70 ± 1.030.119
lnTP (ms2)4.98 ± 1.044.84 ± 0.920.5115.37 ± 0.964.80 ± 0.970.020
UGT1A4
 rs2011425 
T/TG/T, G/GP
7318 
lnLF (ms2)4.14 ± 1.075.06 ± 1.040.001 a
lnHF (ms2)3.59 ± 0.933.86 ± 1.200.378
lnTP (ms2)4.82 ± 0.985.35 ± 0.950.042
ABCB1
 rs1045642rs1128503
C/CC/T, T/TPT/TC/T, C/CP
2467 4348 
lnLF (ms2)4.27 ± 1.194.34 ± 1.100.8034.26 ± 1.074.37 ± 1.170.649
lnHF (ms2)3.97 ± 1.123.75 ± 1.160.4233.69 ± 1.193.91 ± 1.120.370
lnTP (ms2)4.96 ± 1.034.92 ± 0.980.8454,85 ± 1.015.00 ± 0.980.486
ABCB1
 rs2032582rs2235048
G/GG/A•T, A•T/A•TPT/TC/C, C/TP
1675 2467 
lnLF (ms2)4.11 ± 1.074.36 ± 1.130.4194.27 ± 1.194.34 ± 1.100.803
lnHF (ms2)3.80 ± 1.443.81 ± 1.090.9773.97 ± 1.123.75 ± 1.160.423
lnTP (ms2)4.83 ± 1.064.95 ± 0.980.6654.96 ± 1.034.92 ± 0.980.845
  1. Data are presented as mean ± standard deviation values
  2. ln natural log-transformed, HF High frequency, LF Low frequency, TP Total power
  3. a Significant difference (p < 0.007; Student’s t-test)