Rare and common variants analysis of the EMB gene in patients with schizophrenia

Table 2 Detailed information of rare mutations detected in this study

Variants	Variants status	SIFT	Polyphen-2	MutationTaster	Novel or not	Individuals	Gender	group
c.712C > T/p.(Arg238Cys)	Heterozygous	D	D	D	rs749613196	55S0720	Female	SCZ
c.393C > G/p.(Ile131Met)	Heterozygous	T	D	N	novel	QLS422	Male	SCZ
c.353C > T/p.(Ala118Val)	Heterozygous	T	B	N	rs749459608	QLS027	Male	SCZ
c.487G > A/p.(Gly163Arg)	Heterozygous	D	D	N	rs553167245	55S0033	Male	SCZ
						DI128	Female	SCZ
						Q17030	Female	control
						Q16488	Male	control
c.278C > G/p.(Ser93Cys)	Heterozygous	T	B	N	rs148226429	QLS295	Male	SCZ
						55S0268、QLS255	Female	SCZ
						Q16484	Male	control
c.197A > G/p.(Glu66Gly)	Heterozygous	T	B	N	novel	Q17228	Female	control
c.154G > A/p.(Ala52Thr)	Heterozygous	T	B	N	rs766190226	Q16630	Male	control

SCZ Schizophrenia, D Deleterious for SIFT_pred,Probably damaging for Polyphen-2_pred, disease_causing for MutationTaster_pred; T Tolerated, B Benign