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Table 3 Association results of 6 common variants

From: Rare and common variants analysis of the EMB gene in patients with schizophrenia

SNP ID

Group

Allele frequency

Allelic P

Corrected Pa

OR

95% CI

Genotype frequency

Genotypic P

Corrected Pa

rs35327819

 

-

C

    

-/-

-/C

C/C

  

chr5:50396796

SCZ

1690(0.494)

1730(0.505)

0.015*

0.179

1.147

[1.026~1.281]

430(0.251)

830(0.485)

450(0.263)

0.047*

0.346

Control

1040(0.528)

928(0.471)

    

288(0.292)

464(0.471)

232(0.235)

  

rs3933097

 

T

G

    

T/T

T/G

G/G

  

chr5:50398749

SCZ

1973(0.573)

1467(0.426)

1.98e-07**

3.82e-06**

1.354

[1.208~1.518]

571(0.331)

831(0.483)

318(0.184)

1.64e-06**

3.18e-05**

Control

1268(0.645)

696(0.354)

    

413(0.420)

442(0.450)

127(0.129)

  

rs13172025

 

G

A

    

G/G

G/A

A/A

  

chr5:50402346

SCZ

1535(0.480)

1657(0.519)

0.074

 

1.111

[0.989~1.248]

384(0.240)

767(0.480)

445(0.278)

0.199

 

Control

895(0.507)

869(0.492)

    

239(0.270)

417(0.472)

226(0.256)

  

rs199737787

 

C

A

    

C/C

C/A

   

chr5:50403159

SCZ

3399(0.995)

17(0.004)

0.018*

0.182

4.881

[1.126~21.15]

1691(0.990)

17(0.009)

 

0.018*

0.216

Control

1952(0.998)

2(0.001)

    

975(0.997)

2(0.002)

   

rs184038560

 

A

G

    

A/A

G/A

   

chr5:50403449

SCZ

3030(0.990)

28(0.009)

0.096

 

0.636

[0.372~1.089]

1501(0.981)

28(0.018)

 

0.095

 

Control

1792(0.985)

26(0.014)

    

883(0.971)

26(0.028)

   

rs72751723

 

G

T

    

G/G

G/T

T/T

  

chr5:50441389

SCZ

3145(0.900)

349(0.099)

0.664

 

0.960

[0.800~1.152]

1417(0.811)

311(0.178)

19(0.010)

0.843

 

Control

1757(0.896)

203(0.103)

    

787(0.803)

183(0.186)

10(0.010)

  
  1. SCZ Schizophrenia, SNP Single nucleotide polymorphism, OR Odds ratio, CI Confidence interval
  2. aFDR correction
  3. * P-values < 0.05; ** P-values < 0.01