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Table 2 Differentially expressed proteins between major depressive disorder and bipolar disorder

From: Comparison of serum protein profiles between major depressive disorder and bipolar disorder

Majority protein IDsProtein namesGene namesFold changeaStudent’s t-test statistics (t)p-valueb
Overexpressed in MDD
 P51149;C9J592;C9J8S3Ras-related protein Rab-7aRAB7A2.7295.9754.3 * 10−6
 E9PF63;O75116Rho-associated protein kinase 2ROCK22.3214.7828.0 * 10−5
 P01763Ig heavy chain V-III region WEAIGHV3–481.2053.6680.001
 P08571;D6RFL4Monocyte differentiation antigen CD14;Monocyte differentiation antigen CD14, urinary form;Monocyte differentiation antigen CD14, membrane-bound formCD141.2662.8750.009
 P23083Ig heavy chain V-I region V35IGHV10R15–12.1032.7390.011
 A0A075B6Q5Ig heavy variable 3–64IGHV3–642.2522.6980.013
 P01780Ig heavy chain V-III region JONIGHV3–70.9412.4040.025
Overexpressed in BD
 E7ESC6;Q9UIA9Exportin-7XPO7−2.999−4.5201.5 * 10−4
 P03950AngiogeninANG−1.714−3.6360.001
 A0A075B6J4Ig lambda variable 3–25IGLV3–25−2.550−3.3260.003
 Q96Q89–4;Q96Q89–3;Q96Q89;Q96Q89–2Kinesin-like protein KIF20BKIF20B−1.298−2.7180.012
 A0A096LPE2;P35542;A0A087X0E2Serum amyloid A-4 protein; Serum amyloid A proteinSAA2-SAA4;SAA4−0.660−2.6400.015
 P05160Coagulation factor XIII B chainF13B−1.120−2.3150.030
 D6REX5;P49908;D6RIS9Selenoprotein PSEPP1;SELENOP−0.881−2.0880.048
  1. Abbreviations: MDD major depressive disorder, BD bipolar disorder
  2. aFold change calculated by the difference of the logarithmic(2) transferred intensity
  3. bBoldface p-values are significant when adjusting for multiple comparison by using the Benjamini-Hochberg FDR adjusted p-value