Minocycline as adjunctive treatment for treatment-resistant depression: study protocol for a double blind, placebo-controlled, randomized trial (MINDEP2)

Table 2 Assessment Schedule

Assessment	Screening	Baseline	Week 2	Week 4	Week 6	Week 8	Week 10	Week 12	Ad hoc
Medical Confirmation of Eligibility, SCID-5	x
Clinical Bloodwork	x
Randomization	x	x
HRSD-17	x	x	x		x			x
CGI		x	x		x			x
GAD-7		x	x		x			x
WHOQOL-BREF		x	x		x			x
Minocycline dispensed		x	x		x
TAU/Concomitant medication		x	x		x			x
Adverse Event Checks		x	x		x			x	x
Physical health measures		x
Biomarkers (CRP, cytokines)		x						x
Telephone contact				x		x	x	x	x

ISSN: 1471-244X