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Table 2 Significant cortical regions identified in group comparisons or within-group correlation analyses

From: Gray-matter structure in long-term abstinent methamphetamine users

 

Peak pvertex

pcluster

Size (mm2)

Talairach coordinates

Annotations

X

Y

Z

Group comparisons a

Thickness

 User>Control

0.00016

0.010

1038.38

−20

59.3

1.1

L-rostralmiddlefrontal

 

0.00097

0.004

1181.39

−9.7

18.7

41.5

L-superiorfrontal

 

0.00061

0.0001

1659.83

7.1

56.9

−14.8

R-frontalpole, R-superiorfrontal

Volume

 User<Control

0.00016

0.043

864.62

33.4

−75.4

10.2

R-lateraloccipital

Correlations

 Thickness-ABS b

0.00015(+)

0.004

1230.94

45.2

−2.7

−16.4

R-superiortemporal, R-insula

 Volume-ABS b

0.00007(+)

0.004

1183.08

−36.5

−0.4

15.2

L-insula

0.00074(+)

0.009

1091.21

38.1

−0.1

1.8

R-insula

 Thickness- MA use c

0.00019(−)

0.0001

2796.16

5.7

− 87.8

−0.2

R-lingual, R-pericalcarine

 Volume-MA use c

0.00126(−)

0.009

1101.37

12.4

−79.7

−2.8

R-lingual, R-pericalcarine

  1. Whole-brain vertex-wise analyses. Vertex-wise p < 0.05, corrected for multiple comparisons using Monte Carlo Null-Z Simulation (5000 times, cluster p < 0.05). (+) or (−) showed positive or negative correlation respectively
  2. a ANCOVA with sex, age and total intracranial volume (ICV) controlled
  3. b Partial correlation with sex, age, age at onset of methamphetamine (MA) use, duration of MA use (MA use) and ICV controlled
  4. c Partial correlation with sex, age, age at onset of MA use, duration of abstinence from MA (ABS) and ICV controlled