Skip to main content

Table 4 Neurodevelopmental and neuropsychiatric morbidity (NE, not evaluated)

From: Comprehensive phenotyping of neuropsychiatric traits in a multiplex 3q29 deletion family: a case report

PhenotypeII-1 (Proband)II-2 (8 yo male)II-3 (4 yo male)I-1 (39 yo male)Reported Frequency in 3q29 deletion syndrome
General psychopathologyADHD, combined typeADHD, Combined type;
Disruptive Mood Dysregulation Disorder;
Conduct Disorder with Childhood Onset
ADHD, hyperactive typeADHD, inattentive typeADHD: NE
Prodrome/psychosisAttenuated Psychosis SyndromeNESchizoaffective disorderPsychosis: 5%3
Executive function
T-score (%tile)
Clinically Significant Deficits 86 (> 99)Clinically Significant Deficits
88 (> 99)
NEClinically Significant Deficits
73 (97)
NE
Adaptive behavior
Standard Score (%tile)
Significant Delays
65 (1)
Significant Delays
59 (< 1)
Significant Delays
68 (2)
Significant Delays
61 (< 1)
Global Devel Delay 41%3
Visual-motor integration
Standard Score (%tile)
Average Range
92 (30)
Significant Delays
77 (6)
Low
83 (13)
Low
83 (13)
NE
AnxietySeparation Anxiety; Specific Phobia of the DarkNEPanic disorder; social anxiety disorderAnxiety: 19%3
AutismAutism: 26%3
Cognitive Ability
Standard Score (%tile)
Below Average
82 (12)
Low
79 (8)
Average
96 (39)
Average
94 (34)
Intellectual disability: 92%2