Variables | N | Deaths | Person- years | Incidence rate | Age and sex -adjusted | Multivariate-adjusteda | Multivariate-adjustedb |
---|---|---|---|---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | |||||
Baseline MMSE score | Â | Â | Â | Â | 0.91 (0.88, 0.94)*** | 0.91 (0.88, 0.94)*** | 0.93 (0.90, 0.97)*** |
Baseline cognitive status | |||||||
 Normal | 779 | 108 | 5244.40 | 20.59 | 1.00 | 1.00 | 1.00 |
 Impaired | 142 | 52 | 849.34 | 61.22 | 2.60 (1.81, 3.73) *** | 2.53 (1.76, 3.65)*** | 2.08 (1.43, 3.01)*** |
 Total | 921 | 160 | 6093.74 | 26.26 |  |  |  |
One-year transition in cognitive status | |||||||
 Normal-normal | 393 | 31 | 2368.37 | 13.09 | 1.00 | 1.00 | 1.00 |
 Normal-impaired | 55 | 9 | 315.73 | 28.51 | 2.19 (1.02, 4.71)* | 2.36 (1.07, 5.19)* | 2.01 (0.88, 4.59) |
 Impaired-normal | 31 | 9 | 168.36 | 53.46 | 3.27 (1.51, 7.09)** | 3.60 (1.64, 7.90)** | 2.87 (1.25, 6.56)* |
 Impaired-impaired | 38 | 13 | 196.41 | 66.19 | 4.83 (2.29, 10.15)** | 5.26 (2.45, 11.32)*** | 3.79 (1.64, 8.73)** |