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Table 2 Univariate and multivariate analyses of risk factors for psychiatric disorders

From: Psychiatric disorders risk in patients with iron deficiency anemia and association with iron supplementation medications: a nationwide database analysis

 Crude HR
(95% CI)
p-valueAdjusted HR
(95% CI)
p-value
IDA1.36 (1.31–1.41)<  0.0011.52 (1.45–1.59)<  0.001
Age
501.00 1.00 
  > 501.04 (1.01–1.08)0.0171.04 (1.00–1.09)0.081
Gender
 Female1.00 1.00 
 Male0.71 (0.68–0.74)<  0.0010.65 (0.62–0.68)<  0.001
Income level
 Low1.00 1.00 
 Intermediate0.99 (0.96–1.02)0.5431.00 (0.96–1.03)0.846
 High0.87 (0.81–0.93)<  0.0010.90 (0.84–0.97)0.005
Comorbidity
 Hypertension1.20 (1.15–1.25)<  0.0011.13 (1.07–1.19)<  0.001
 DM1.07 (1.02–1.13)0.0130.88 (0.82–0.94)<  0.001
 Dyslipidemia1.30 (1.24–1.37)<  0.0011.23 (1.16–1.30)<  0.001
 Hyperthyroidism1.34 (1.21–1.49)<  0.0011.19 (1.07–1.33)0.001
 Hypothyroidism1.33 (1.11–1.60)0.0021.11 (0.92–1.33)0.272
 COPD1.26 (1.20–1.32)<  0.0011.21 (1.16–1.27)<  0.001
 Stroke1.11 (1.04–1.19)0.0030.95 (0.88–1.03)0.205
 CAD1.27 (1.21–1.34)<  0.0011.13 (1.06–1.21)<  0.001
 CKD1.05 (0.93–1.18)0.4660.87 (0.77–0.98)0.024
 Cirrhosis0.87 (0.74–1.03)0.1080.82 (0.70–0.97)0.023
 Iron supplementation1.14 (1.10–1.18)<  0.0010.82 (0.78–0.86)<  0.001
Area
 Urban1.00 1.00 
 Suburban0.98 (0.95–1.02)0.3470.98 (0.94–1.02)0.263
 Rural0.92 (0.86–0.99)0.0340.90 (0.84–0.97)0.009
 Remote area0.98 (0.90–1.08)0.6890.96 (0.87–1.05)0.383
  1. DM Diabetes mellitus, CAD Coronary artery disease, CKD Chronic kidney disease, COPD Chronic Obstructive Pulmonary Disease