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Table 2 Univariate and multivariate analyses of risk factors for psychiatric disorders

From: Psychiatric disorders risk in patients with iron deficiency anemia and association with iron supplementation medications: a nationwide database analysis

 

Crude HR

(95% CI)

p-value

Adjusted HR

(95% CI)

p-value

IDA

1.36 (1.31–1.41)

<  0.001

1.52 (1.45–1.59)

<  0.001

Age

 ≦ 50

1.00

 

1.00

 

  > 50

1.04 (1.01–1.08)

0.017

1.04 (1.00–1.09)

0.081

Gender

 Female

1.00

 

1.00

 

 Male

0.71 (0.68–0.74)

<  0.001

0.65 (0.62–0.68)

<  0.001

Income level

 Low

1.00

 

1.00

 

 Intermediate

0.99 (0.96–1.02)

0.543

1.00 (0.96–1.03)

0.846

 High

0.87 (0.81–0.93)

<  0.001

0.90 (0.84–0.97)

0.005

Comorbidity

 Hypertension

1.20 (1.15–1.25)

<  0.001

1.13 (1.07–1.19)

<  0.001

 DM

1.07 (1.02–1.13)

0.013

0.88 (0.82–0.94)

<  0.001

 Dyslipidemia

1.30 (1.24–1.37)

<  0.001

1.23 (1.16–1.30)

<  0.001

 Hyperthyroidism

1.34 (1.21–1.49)

<  0.001

1.19 (1.07–1.33)

0.001

 Hypothyroidism

1.33 (1.11–1.60)

0.002

1.11 (0.92–1.33)

0.272

 COPD

1.26 (1.20–1.32)

<  0.001

1.21 (1.16–1.27)

<  0.001

 Stroke

1.11 (1.04–1.19)

0.003

0.95 (0.88–1.03)

0.205

 CAD

1.27 (1.21–1.34)

<  0.001

1.13 (1.06–1.21)

<  0.001

 CKD

1.05 (0.93–1.18)

0.466

0.87 (0.77–0.98)

0.024

 Cirrhosis

0.87 (0.74–1.03)

0.108

0.82 (0.70–0.97)

0.023

 Iron supplementation

1.14 (1.10–1.18)

<  0.001

0.82 (0.78–0.86)

<  0.001

Area

 Urban

1.00

 

1.00

 

 Suburban

0.98 (0.95–1.02)

0.347

0.98 (0.94–1.02)

0.263

 Rural

0.92 (0.86–0.99)

0.034

0.90 (0.84–0.97)

0.009

 Remote area

0.98 (0.90–1.08)

0.689

0.96 (0.87–1.05)

0.383

  1. DM Diabetes mellitus, CAD Coronary artery disease, CKD Chronic kidney disease, COPD Chronic Obstructive Pulmonary Disease