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Table 3 Risk for all-cause disability pension (DP) among patients with treatment-resistant depression (TRD) vs. matched comparators with treatment for depression, stratified by matching factors. Unadjusted and adjusted hazard ratios (HR) with 95% confidence intervals (CI)

From: Risk and risk factors for disability pension among patients with treatment resistant depression– a matched cohort study

 Unadjusted HR (95% CI)Adjusted HR (95% CI)a
All1.90 (1.72–2.11)2.07 (1.83–2.35)
Sex
 Men1.77 (1.52–2.08)1.84 (1.50–2.24)
 Women2.00 (1.75–2.29)2.29 (1.94–2.71)
Age (years)b
 18–292.31 (1.90–2.82)2.50 (1.97–3.16)
 30–491.80 (1.54–2.10)2.05 (1.68–2.50)
 50–691.61 (1.32–1.97)1.85 (1.39–2.46)
Type of living area
 Small municipality2.03 (1.66–2.47)2.41 (1.83–3.17)
 Medium-sized municipality1.49 (1.26–1.76)1.43 (1.13–1.80)
 Large city2.27 (1.91–2.70)2.62 (2.10–3.28)
History of depression diagnosisc
 Yes1.78 (1.39–2.28)2.12 (1.50–2.99)
 No1.93 (1.72–2.16)2.13 (1.85–2.45)
  1. aAdjusted for attained educational level, marital/ parental status, country of birth, long-term sickness absence, unemployment, anxiety disorders, personality disorders, and other psychiatric disorders, substance use disorder, history of self-harm/suicide attempt and Charlson’s Comorbidity index
  2. bAt time of first antidepressant prescription
  3. cICD-10 diagnosis F32-F33