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Table 3 Risk for all-cause disability pension (DP) among patients with treatment-resistant depression (TRD) vs. matched comparators with treatment for depression, stratified by matching factors. Unadjusted and adjusted hazard ratios (HR) with 95% confidence intervals (CI)

From: Risk and risk factors for disability pension among patients with treatment resistant depression– a matched cohort study

 

Unadjusted HR (95% CI)

Adjusted HR (95% CI)a

All

1.90 (1.72–2.11)

2.07 (1.83–2.35)

Sex

 Men

1.77 (1.52–2.08)

1.84 (1.50–2.24)

 Women

2.00 (1.75–2.29)

2.29 (1.94–2.71)

Age (years)b

 18–29

2.31 (1.90–2.82)

2.50 (1.97–3.16)

 30–49

1.80 (1.54–2.10)

2.05 (1.68–2.50)

 50–69

1.61 (1.32–1.97)

1.85 (1.39–2.46)

Type of living area

 Small municipality

2.03 (1.66–2.47)

2.41 (1.83–3.17)

 Medium-sized municipality

1.49 (1.26–1.76)

1.43 (1.13–1.80)

 Large city

2.27 (1.91–2.70)

2.62 (2.10–3.28)

History of depression diagnosisc

 Yes

1.78 (1.39–2.28)

2.12 (1.50–2.99)

 No

1.93 (1.72–2.16)

2.13 (1.85–2.45)

  1. aAdjusted for attained educational level, marital/ parental status, country of birth, long-term sickness absence, unemployment, anxiety disorders, personality disorders, and other psychiatric disorders, substance use disorder, history of self-harm/suicide attempt and Charlson’s Comorbidity index
  2. bAt time of first antidepressant prescription
  3. cICD-10 diagnosis F32-F33