Table 3 Frequency of QT prolonging drugs and their therapeutic classes along with TdP risk categories among patients with prolonged QTc interval
Therapeutic class | TdP risk a | QT prolonging drugs (ATC Code) | n (%) b |
|---|---|---|---|
Antidepressants (n = 13) | Known (n = 4) | Escitalopram (N06AB10) | 4 (17.4) |
Possible (2) | Clomipramine (N06AA04) | 1 (4.3) | |
Venlafaxine (N06AX16) | 1 (4.3) | ||
Conditional (7) | Sertraline (N06AB06) | 3 (13) | |
Fluoxetine (N06CA03) | 2 (8.7) | ||
Fluvoxamine (N06AB08) | 1 (4.3) | ||
Paroxetine (N06AB05) | 1 (4.3) | ||
Antipsychotics (5) | Known (2) | Haloperidol (N05AD01) | 1 (4.3) |
Levosulpiride (N05AL07) | 1 (4.3) | ||
Possible (2) | Risperidone (N05AX08) | 1 (4.3) | |
Aripiprazole (N05AX12) | 1 (4.3) | ||
Conditional (1) | Olanzapine (N05AH03) | 1 (4.3) | |
Proton pump inhibitors (2) | Conditional (2) | Esomeprazole (A02BC05) | 2 (8.7) |
Diuretics (2) | Conditional (2) | Hydrochlorothiazide (C03AA03) | 1 (4.3) |
Furosemide (C03CA01) | 1 (4.3) | ||
Antinausea (1) | Known (1) | Domperidone (A03FA03) | 1 (0.9) |