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Table 4 Logistic regression analysis

From: Prevalence of QTc interval prolongation and its associated risk factors among psychiatric patients: a prospective observational study

Variables

Univariate analysis

Multivariate analysis

OR (95% CI)

p-value

OR (95% CI)

p-value

Gender

 Female

Reference

 

Reference

 

 Male

3.2 (1.1–9.5)

0.03

5.6 (1.6–19.8)

0.007

Age (years)

  ≤ 20

2.1 (0.5–7.7)

0.26

2.8 (0.6–11.3)

0.15

 21–30

Reference

 

Reference

 

 31–40

1.1 (0.2–4.5)

0.87

1.3 (0.2–5.9)

0.71

  > 40

2.1 (0.6–7.3)

0.20

2.5 (0.6–9.1)

0.16

All prescribed drugs

 1

Reference

 

Reference

 

 2–3

2.9 (0.3–22.7)

0.32

5.5 (0.5–57.2)

0.14

  > 3

3.5 (0.4–28.9)

0.25

8.5 (0.6–111.3)

0.10

QT prolonging Drugs

 1

Reference

 

Reference

 

  ≥ 2

1.7 (0.7–3.9)

0.22

1.9 (0.6–5.1)

0.23

Medical illnesses

 Psychosis

1.2 (0.2–5.1)

0.84

5.7 (0.7–41.8)

0.08

 Obsessive compulsive disorder

2.1 (0.4–10.1)

0.32

2.3 (0.2–19.9)

0.45

 Schizophrenia

1.04 (0.1–8.2)

0.97

8.2 (0.7–95.1)

0.09

 Major depression

0.8 (0.3–1.9)

0.67

3.8 (0.7–20.4)

0.11

 Manic depressive psychosis

1.6 (0.4–5.6)

0.47

2.3 (0.3–13.6)

0.35

Co-morbid illnesses

 Hypertension

1.3 (0.3–4.5)

0.69

0.5 (0.1–2.9)

0.50

 Antipsychotics

1.6 (0.6–3.6)

0.28

1.9 (0.4–9.3)

0.38

 Proton pump inhibitors

0.3 (0.04–2.4)

0.26

6.6 (0.7–62.5)

0.09

 Other drugs

1.8 (0.3–8.3)

0.44

0.6 (0.1–3.9)

0.59