Demographics & Characteristic Features | Clozapine-Induced Fever | Clozapine-Induced Hypothermia |
---|---|---|
Onset | < 1 month appears to be greatest risk, but may occur at any time or with dose increases [24,25,26] | |
Dose Related | Unlikely, but risk possibly increased with overdose [23, 24] | |
Titration Related | Unknown | |
Concomitant Medication(s) Which May Increase Risk | Valproic acid, benzodiazepines, additional antipsychotics [24] | |
Sex Category | Male>female (~ 1.5:1) [24] | |
Age (years) | Average age ~ 41 | Average age ~ 46 (~ 63% are 40+, with ~ 25.8% being 60+) [24] |
Seen on Rechallenge | Unknown |