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Table 2 The neuropsychological test battery

From: Case report: cognitive performance in an extreme case of anorexia nervosa with a body mass index of 7.7

Instrument

Variables

Description

Higher/lower scores indicating improvement

Reliability

Wechsler Memory Scale III (WMS-III)1

Logical memory I

Task: History recitation

Higher

Adequate internal consistency: 0.88a

Adequate test – retest: 0.77b

SEM: 1.04a

Sdiff: 1.47

Logical Memory II

Task: Delayed history recitation

Higher

Low internal consistency:

0.84a

Adequate test – retest: 0.77b

SEM: 1.20a

Sdiff: 1.70

Verbal Paired Associates I

Task: Word pairing

Higher

Adequate internal consistency: 0.95a

Adequate test – retest: 0.77b

SEM: 0.67a

Sdiff: 0.95

Verbal Paired Associates II

Task: Delayed word pairing

Higher

Adequate internal consistency: 0.88a

Adequate test – retest: 0.73b

SEM: 1.04a

Sdiff: 1.47

Faces I

Task: Face recognition among other faces

Higher

Low internal consistency:

0.77a

Low test – retest: 0.64b

SEM: 1.44a

Sdiff: 2.04

Faces II

Task: Delayed face recognition

Higher

Low internal consistency: 0.83a

Low test – retest: 0.58b

SEM: 1.24a

Sdiff: 1.75

Family Pictures I

Task: Picture recall

Higher

Adequate internal consistency: 0.86a

Low test – retest: 0.61b

SEM: 1.12a

Sdiff: 1.58

Family Pictures II

Task: Delayed picture recall

Higher

Adequate internal consistency: 0.85a

Low test – retest: 0.67b

SEM: 1.16a

Sdiff: 1.64

Letter-Number Sequencing

Task: Recall and ordering letters and numbers

Higher

Low internal consistency:

0.75a

Low test – retest: 0.61b

SEM: 1.50a

Sdiff: 2.12

Spatial Span

Task: Visual pointing recall

Higher

Low internal consistency:

0.82a

Low test – retest: 0.65b

SEM: 1.27a

Sdiff: 1.80

Auditory Immediate Index

Index: Measuring auditory immediate memory

Higher

Adequate internal consistency: 0.93a

Adequate test – retest: 0.84b

SEM: 3.97a

Sdiff: 5.61

Auditory Delayed Index

Index: Measuring auditory delayed memory

Higher

Adequate internal consistency: 0.90a

Adequate test – retest: 0.82b

SEM: 4.74a

Sdiff: 6.70

Visual Immediate Index

Index: Measuring visual immediate memory

Higher

Adequate internal consistency: 0.85a

Adequate test – retest: 0.74b

SEM: 5.81a

Sdiff: 8.22

Visual Delayed Index

Index: Measuring visual delayed memory

Higher

Adequate internal consistency: 0.87a

Adequate test – retest: 0.74b

SEM: 5.41a

Sdiff: 7.65

Immediate Memory index

Index: Measuring immediate memory

Higher

Adequate internal consistency: 0.92a

Adequate test – retest: 0.84b

SEM: 4.24a

Sdiff: 3.17

Auditory Recognition Delayed Index

Index: Measuring recognition

Higher

Low internal consistency:

0.74a

Low test – retest: 0.60b

SEM: 7.65a

Sdiff: 10.82

General Memory Index

Index: A global measure of delayed memory

Higher

Adequate internal consistency: 0.93a

Adequate test – retest: 0.87b

SEM: 3.97a

Sdiff: 5.61

Working Memory Index

Index: Measuring working memory

Higher

Adequate internal consistency: 0.85a

Adequate test – retest: 0.70b

SEM: 5.81a

Sdiff: 8.22

Processing Speed Index (PSI) of the Wechsler Adult Intelligence Scale IV (WAIS-IV)2

Symbol Search

Task: Search for symbols in rows of symbols

Higher

Low internal consistency: 0.73a

Adequate test – retest: 0.75c

SEM: 1.56a

Sdiff: 2.21

Symbol Search errors

Lower

Coding

Task: Write correct symbols under numbers

Higher

Internal consistency: 0.84a

Adequate test – retest: 0.83c

SEM: 1.20a

Sdiff: 1.70

Coding errors

Lower

Processing Speed Index

Index: Measuring processing speed (and attention)

Higher

Adequate internal consistency:

0.87a

Adequate test – retest: 0.87c

SEM: 5.41a

Sdiff: 7.65

d2-R Test of Attention – Revised3

Processed Targets

Task: Search for d’s with marks in rows of letters with marks

Higher

Errors

Lower

Accuracy (% errors)

Lower

Corrected total score

Measuring attention, (and processing speed and response inhibition)

Higher

High test – retest: 0.87

SEM: 40.1d

Sdiff: 56.71

Concentration Performance

Measuring concentration

Higher

High test – retest: 0.91

SEM: 17.6d

Sdiff: 24.89

Delis-Kaplan Executive Function System (D-KEFS)4:

 

Verbal Fluency Test

Condition 1: Phonemic/ Letter Fluency

Task: Words with specific first letter

Measuring word fluency

Higher

High internal consistency: 0.90e

Moderate test – retest: 0.76f

SEM: 0.97e

Sdiff: 1.37

Condition 2: Semantic/ Category Fluency

Task: Animals and boy’s names

Measuring word fluency

Higher

Moderate internal consistency: 0.76e

Good test – retest: 0.81f

SEM: 1.48e

Sdiff: 2.09

Condition 3: Category Switching

Task: Switch between furniture and fruits

Measuring cognitive flexibility

Higher

Moderate internal consistency: 0.68e

Low test – retest: 0.49f

SEM: 1.71e

Sdiff: 2.42

Repetition Errors

Lower

Category Errors

Lower

Design Fluency Test

Condition 1: Filled Dot

Task: Draw different designs

Measuring design fluency

Higher

Moderate test – retest: 0.62f

SEM: 1.94g

Sdiff: 2.74

Condition 2: Empty Dots Only

Task: Draw different designs without the use of filled dots

Measuring design fluency and response inhibition

Higher

Moderate test – retest: 0.73f

SEM: 1.98g

Sdiff: 2.80

Condition 3: Switching

Task: Switch between filled and empty dots

Measuring cognitive flexibility

Higher

Low test – retest: 0.22f

SEM: 2.47g

Sdiff: 3.49

Repetition Errors

Lower

Category Errors

Lower

Trail Making Test

Condition 1: Visual search

Task: Cross 3’s among numbers and letters

Measuring attention, and processing speed

Lower

Low test – retest: 0.55f

Condition 2: Numbers

Task: Draw line between numbers in order among numbers and letters

Measuring attention and processing speed

Lower

Low test – retest: 0.54f

Condition 3: Letters

Task: Draw line between letters in order among numbers and letters

Measuring attention and processing speed

Lower

Low test – retest: 0.48f

Condition 4: Number-Letter

Task: Switch between numbers and letters

Measuring cognitive flexibility

Lower

Low test – retest: 0.36f

Condition 4 Errors

Lower

Condition 5: Motor Speed

Lower

Moderate test – retest: 0.73f

Combined Number + Letter Sequencing

Lower

Moderate internal consistency: 0.78e

Moderate test – retest: 0.64f

SEM: 1.41g

Sdiff: 1.99

Wisconsin Card Sorting Test Revised and Expanded (WCST)5

Trials Administered

Task: Matching cards to key cards based on color, form, or number

Lower

Correct trials

Higher

Errors

Lower

Generalizability coefficient: 0.71

SEM: 8.08

Perseverative Responses

Measuring cognitive inflexibility

Lower

Generalizability coefficient: 0.53

SEM: 10.28

Perseverative Errors

Measuring cognitive inflexibility

Lower

Generalizability coefficient: 0.52

SEM: 10.39

Non-perseverative Errors

Lower

Generalizability coefficient: 0.72

SEM: 7.94

Conceptual Level Responses

Higher

Categories Completed

Higher

Failure to Maintain Set

Lower

  1. 1 Information from WAIS-III WMS-III Technical Manual (2002), re-test interval WMS-III = 35.6 days; 2 Information from WAIS-IV Technical and Interpretive Manual (2008), re-test interval WAIS-IV = 22 days; 3 Information from d2 Test of Attention in Danish d2-testen – en vurdering af opmærksomhed of koncentration (2006), re-test interval d2 test = 8–9 weeks; 4 Information from D-KEFS Technical Manual (2001), re-test interval D-KEFS = 25 days; 5 Information from Wisconsin Card Sorting Test Manual – Revised and Expanded (1993), re-test interval WCST = 32.61 days
  2. SEM Standard errors of measurement (reported in scaled-score units for subtests (for WMS-III, WAIS_IV, and D-KEFS), in index units for index scores (for WMS and WAIS), and in total score units (for d2 test and WCST))
  3. Sdiff Estimated standard error of the difference scores (calculated based on Iverson and Grant (2001))
  4. a Reported in relation to age 35–44 years; b Reported in relation to age 16–54 years; c Reported in relation to age 30–54 years; d Reported for whole sample 20–60 years; e Reported in relation to age 30–39 years; f Reported in relation to age 20–49 years; g Reported for whole sample 8–89 years