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Table 5 Mean, standard deviation, range and between-groups comparison of neuropsychological variables

From: Cognitive performance in children and adolescents at high-risk for obsessive-compulsive disorder

 

High Risk

n = 18

Non-OCD Control

n = 31

  

Neuropsychological measure

Mean

(SD)

Mean

(SD)

t-test

p-value

IQ

 Total (WASI)

103.5

(12.2)

105.6

(13.4)

0.07

0.938

 Verbal (WASI)

112.5

(15.2)

110.5

(15.4)

1.02

0.313

 Performance (WASI)

93.9

(9.8)

99.7

(10.1)

−1.28

0.207

 Verbal-Performance Discrepancya

18.61

(13.2)

10.8

(11.6)

2.11

0.043n

ATTENTION

 RAVLT span A

6.2

(1.5)

6.4

(1.6)

−0.49

0.622

 RAVLT span B

5.7

(1.9)

5.6

(1.5)

0.19

0.843

 TMT 1st condition omissions

0.2

(0.7)

0.2

(0.4)

−0.08

0.936

 TMT 4th condition sequence errors

0.4

(1.0)

0.4

(0.6)

−0.15

0.879

 DFT 1 e DFT 2 - %errors

.12

(0.2)

.04

(0.1)

1.47

0.152

 WCST failures to maintain set

1.1

(1.2)

1.2

(1.0)

−0.30

0.764

 Go-NoGo omissions

3.6

(6.5)

2.6

(4.0)

0.78

0.439

MOTOR AND PROCESSING SPEED

 CWIT color naming time

42.1

(7.8)

39.9

(9.1)

0.86

0.390

 CWIT word reading time

27.8

(4.3)

28.9

(7.4)

−0.67

0.503

 TMT 5th condition time

47.1

(21.5)

34.0

(14.4)

2.27

0.030n

 Grooved dominant hand time

89.5

(24.9)

83.7

(15.0)

0.90

0.376

 Grooved non-dominant hand time

95.8

(28.9)

92.4

(19.0)

0.44

0.662

VISUOCONSTRUCTIVE ABILITIES

 Block Design Test

19.0

(9.5)

25.6

(12.4)

−2.08

0.042n

 ROCF total score – copy

28.8

(6.5)

30.5

(3.7)

−0.59

0.558

VISUOSPATIAL MEMORY

 CBTT forward hits

6.5

(1.5)

8.1

(2.3)

−2.94

0.005*

 ROCF immediate recall

18.7

(6.7)

19.2

(5.4)

−0.26

0.792

 ROCF delayed recall

18.3

(6.8)

18.4

(5.6)

−0.08

0.930

VERBAL MEMORY

 DST forward hits

7.5

(1.3)

7.0

(2.1)

1.15

0.254

 RAVLT immediate recall

9.9

(2.2)

10.3

(2.6)

−0.55

0.583

 RAVLT delayed recall

9.9

(2.3)

10.3

(2.9)

−0.21

0.828

WORKING MEMORY

 CBTT backward hits

5.9

(1.2)

7.0

(1.7)

−2.31

0.026n

 DST backward hits

4.8

(1.7)

4.7

(1.7)

0.25

0.797

COGNITIVE FLEXIBILITY

 WCST Perseverative errors

10.4

(3.5)

9.8

(3.8)

0.46

0.642

 WCST categories

2.4

(1.2)

2.5

(1.2)

−0.10

0.913

 DFT %Perseverative errors

.13

(0.2)

.03

(0.1)

0.74

0.464

 TMT 4–5

96.2

(86.3)

84.3

(50.6)

0.15

0.877

 Brixton hits

36.6

(8.5)

40.0

(4.1)

−1.16

0.254

INHIBITORY CONTROL

 Go-NoGo Commission errors

8.8

(3.9)

8.5

(3.7)

0.25

0.800

 CWIT 3 errors

2.8

(3.5)

2.0

(2.8)

0.64

0.525

 CWIT 4 errors

2.0

(2.2)

2.5

(3.4)

−0.17

0.863

 CWIT 3–1 time difference

39.1

(18.8)

36.5

(18.0)

0.37

0.709

  1. a The Verbal – Performance difference is calculated by subtracting the performance IQ from the verbal IQ. WASI – Wechsler abbreviated scale of intelligence; RAVLT – Rey auditory verbal learning test; TMT – Trail making test; DFT– Design fluency test; WCST – Wisconsin card sorting test; CWIT – Color-word interference test; ROCF – Rey-Osterrieth complex figure; CBTT – Corsi block-tapping test; DST – Digit span test. n p-value < 0.05 (nominal significance); * p-value < 0.0055 (according to Bonferroni correction)
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BMC Psychiatry

ISSN: 1471-244X

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