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Table 2 Summary of the PICOS concepts in the reviewed publications

From: A meta-review of literature reviews assessing the capacity of patients with severe mental disorders to make decisions about their healthcare

Study

Country

PICOS

  

Population

N

Intervention

Comparator

N

Outcomes

Setting

Eiring Ø et al. 2015, [11]

Norway

Schizophrenia, depression, bipolar disorder, attention deficit hyperactive disorder

1785

Stated preferences by means of willingness to pay, conjoint analysis, discrete choice experiment

None

Relative value placed on treatment outcomes.

Inpatients, outpatients

Hostiuc S et al. 2018, [12]

Romania

Schizophrenia

684

MacArthur Competence Assessment Tool

-Clinical Research

Non-mental illness patients

(control)

548

Differences in MacArthur Competence Assessment Tool measurements and consent to research participation

Inpatients, outpatients

Jeste DV et al. 2006, [13]

United States

Schizophrenia

Range: 6–80

MacArthur Competence Assessment Tool

-Treatment

-Clinical Research

Non-psychiatric comparison subjects

Range: 15–82

Differences on

MacArthur Competence Assessment Tool

Inpatients and outpatients

Larkin A et al. 2017, [14]

United Kingdom

Psychosis

(non-affective psychotic disorder)

1823

Brief Psychiatric Rating Scale.

Positive and negative syndrome scale score

None

Factors that help or hinder treatment decision-making capacity.

Assessment of direction, magnitude, significance and reliability of reported associations

Inpatients and outpatients

Lepping P et al. 2015, [15]

United Kingdom

Psychiatric disorder patients

2483

Any validated tool to assess capacity for making decisions

Non-psychiatric (medical) patients

1710

Incapacity to consent to treatment or admission

Inpatients, outpatients, forensic

Mukherjee D et al. 2014, [16]

United States

Mental illness patients

1813

Iowa Gambling Task

Healthy individuals

Individuals with frontal lesions

3165

First meta-analysis: effectsizes for comparisons between healthy individuals and those with mental illness

Second meta-analysis: raw scores from the IGT across different mental illnesses

Outpatients

Okai D et al. 2007, [17]

United Kingdom

Psychiatric disorder patients

851

Vignettes, 15-item questionnaire, MacArthur Competence Assessment Tool- Treatment, semi-structured interview

None

Capacity to consent to treatment

Inpatients and outpatients

Ruissen AM et al. 2011, [18]

Netherlands

Psychotic and non-psychotic disorder patients

735

MacArthur Competence Assessment Tool

None

Competence and treatment decision and insight

Inpatients and outpatients

Spencer BWJ et al. 2017, [19]

United Kingdom

Schizophrenia and non-affective disorders

Not reported

MacArthur Competence Assessment Tool

-Treatment

-Clinical Research

None

Decision making capacity for treatment and research

Inpatient and outpatients

Wang SB et al. 2017, [20]

Multicountry

Schizophrenia or schizoaffective disorder

422

MacArthur Competence Assessment Tool

-Clinical Research

-Treatment

Healthy controls

304

Decision making capacity

Outpatients

Woodrow A et al. 2018, [21]

United Kingdom

Psychosis

2276

Iowa and Cambridge Gambling Tasks

Healthy controls

1988

Between-group comparison of performance on IGC instruments

Outpatients