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Table 5 Binary logistic regression analysis of significant clinical predictors (Y-BOCS items and factors) of response to rTMS treatment

From: Efficacy and clinical predictors of response to rTMS treatment in pharmacoresistant obsessive-compulsive disorder (OCD): a retrospective study

Predictors Nagelkerke R2 0.46(item-based analysis) Mean±SD item score in NR and (R) Predicted group β Wald df p Odd ratio (e β) 95% CI
Lower Upper
Individual Y-BOCS factors   Non-responders       
Interference due to obsessive thoughts (2) 2.11 ± 0.93 (1.17 ± 0.69)   1.34 9.89 1 0.002 3.83 1.66 8.86
Resistance against compulsions (9) 2.0 ± 1.11 (1.0 ± 0.94)   0.86 7.41 1 0.006 2.38 1.27 4.45
Constant    −3.31 13.06 1 0.01 0.03   
Time occupied by obsession (1) 2.40 ± 1.03 (1.53 ± 0.86)      0.10    
Distress associated with obsessions (3) 2.51 ± 0.74 (1.77 ± 1.07)      0.14    
Resistance against obsessions (4) 1.69 ± 0.90 (1.30 ± 0.79)      0.29    
Control over obsessions (5) 2.51 ± 0.88 (1.67 ± 0.84)      0.21    
Time spent on compulsions (6) 1.77 ± 0.97 (1.07 ± 0.74)      0.68    
Interference due to compulsions (7) 1.86 ± 1.06 (0.97 ± 0.92)      0.96    
Distress associated with compulsions (8) 2.03 ± 1.04 (1.03 ± 1.15)      0.81    
Control over compulsions (10) 2.17 ± 1.12 (1.23 ± 0.97)      0.67    
2-factor Model [57] Disturbance factor (items, 2,3,7,8) 8.51 ± 2.86 (4.93 ± 2.67)   0.51 13.41 1 0.001 1.67 1.27 2.20
Symptom severity factor (items 1,4,5,6,9,10) 12.54 ± 3.76 (7.80 ± 3.72)      0.09    
3-factor model [58] Obsession severity factor (items 1–3,5) 9.54 ± 2.74 (6.13 ± 2.90)   0.37 8.19 1 0.004 1.45 1.12 1.87
Resistance factor (items 4,9) 3.86 ± 1.36 (2.30 ± 1.37)   0.59 5.16 1 0.023 1.82 1.08 3.02
Compulsion severity factor (items 6–8,10) 7.82 ± 3.51 (4.30 ± 3.17)      0.25    
  1. Predicted group = the group coded with value 1 in binary regression analysis; NR non-responders, R responders; Significant results are highlighted (p ≤ 0.05) in bold