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Table 5 Binary logistic regression analysis of significant clinical predictors (Y-BOCS items and factors) of response to rTMS treatment

From: Efficacy and clinical predictors of response to rTMS treatment in pharmacoresistant obsessive-compulsive disorder (OCD): a retrospective study

Predictors Nagelkerke R2 0.46(item-based analysis)

Mean±SD item score in NR and (R)

Predicted group

β

Wald

df

p

Odd ratio (e β)

95% CI

Lower

Upper

Individual Y-BOCS factors

 

Non-responders

      

Interference due to obsessive thoughts (2)

2.11 ± 0.93 (1.17 ± 0.69)

 

1.34

9.89

1

0.002

3.83

1.66

8.86

Resistance against compulsions (9)

2.0 ± 1.11 (1.0 ± 0.94)

 

0.86

7.41

1

0.006

2.38

1.27

4.45

Constant

  

−3.31

13.06

1

0.01

0.03

  

Time occupied by obsession (1)

2.40 ± 1.03 (1.53 ± 0.86)

    

0.10

   

Distress associated with obsessions (3)

2.51 ± 0.74 (1.77 ± 1.07)

    

0.14

   

Resistance against obsessions (4)

1.69 ± 0.90 (1.30 ± 0.79)

    

0.29

   

Control over obsessions (5)

2.51 ± 0.88 (1.67 ± 0.84)

    

0.21

   

Time spent on compulsions (6)

1.77 ± 0.97 (1.07 ± 0.74)

    

0.68

   

Interference due to compulsions (7)

1.86 ± 1.06 (0.97 ± 0.92)

    

0.96

   

Distress associated with compulsions (8)

2.03 ± 1.04 (1.03 ± 1.15)

    

0.81

   

Control over compulsions (10)

2.17 ± 1.12 (1.23 ± 0.97)

    

0.67

   

2-factor Model [57] Disturbance factor (items, 2,3,7,8)

8.51 ± 2.86 (4.93 ± 2.67)

 

0.51

13.41

1

0.001

1.67

1.27

2.20

Symptom severity factor (items 1,4,5,6,9,10)

12.54 ± 3.76 (7.80 ± 3.72)

    

0.09

   

3-factor model [58] Obsession severity factor (items 1–3,5)

9.54 ± 2.74 (6.13 ± 2.90)

 

0.37

8.19

1

0.004

1.45

1.12

1.87

Resistance factor (items 4,9)

3.86 ± 1.36 (2.30 ± 1.37)

 

0.59

5.16

1

0.023

1.82

1.08

3.02

Compulsion severity factor (items 6–8,10)

7.82 ± 3.51 (4.30 ± 3.17)

    

0.25

   
  1. Predicted group = the group coded with value 1 in binary regression analysis; NR non-responders, R responders; Significant results are highlighted (p ≤ 0.05) in bold