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Table 1 Socio-demographics, clinical characteristics and metabolic indictors between patients with and without suicide attempts

From: Potential metabolic monitoring indicators of suicide attempts in first episode and drug naive young patients with major depressive disorder: a cross-sectional study

Variable

MDD without suicide attempt (n = 612)

MDD with suicide attempt (n = 128)

F/X2

P value

Age, mean (SD), y

22.68

4.09

22.98

3.765

0.610

0.435

Course of disease, mean (SD), m

4.58

2.99

5.54

3.85

9.710

0.002**

Gender

 Male, n (%)

236

38.6

51

39.8

  

 Female, n (%)

376

61.4

77

60.2

  

Cultural degree

 Junior high school education level, n (%)

29

4.8

13

10.2

  

 Senior high school education level, n (%)

300

49.0

55

43.0

  

 University education level, n (%)

240

39.2

50

39.0

  

 Postgraduate education level, n (%)

43

7.0

10

7.8

  

Marital status

 Single

384

62.7

86

67.2

  

 Married

228

37.3

42

32.8

  

HAMD, mean (SD)

29.71

2.84

32.08

2.75

74.600

<  0.001 ***

HAMA, mean (SD)

20.03

3.10

23.20

3.47

105.711

<  0.001 ***

Obvious anxiety (HAMA ≥21), n (%)

270

44.1

102

79.7

740

<  0.001 ***

Psychotic symptoms (PANSS ≥15), n (%)

43

7.02

24

18.75

6.643

0.012*

BMI, mean (SD), kg/m2

24.31

1.87

24.14

2.75

0.694

0.405

SBP, mean (SD), mmHg

111.82

9.19

119.42

12.57

62.909

<  0.001***

DBP, mean (SD), mmHg

72.98

5.81

76.63

7.01

38.651

<  0.001***

FBG, mean (SD), mmol/L

5.32

0.61

5.61

0.70

23.145

<  0.001***

Increase (FBG > 6.10 mmol/L), n (%)

66

10.8

29

22.7

  

Normal (3.90–6.10 mmol/L), n (%)

546

89.2

99

77.3

  

TC, mean (SD), mmol/L

5.00

1.07

5.80

1.14

57.461

<  0.001***

Increase (TC ≥ 5.17 mmol/L), n (%)

255

41.6

83

64.8

  

Normal (TC < 5.17 mmol/L), n (%)

357

58.4

45

35.2

  

HDL-C, mean (SD), mmol/L

1.25

0.28

1.12

0.31

20.920

<  0.001***

Decrease (HDL-C < 1.04 mmol/L), n (%)

147

24.0

55

43.0

  

Normal (1.04–2.07 mmol/L), n (%)

465

76.0

73

57.0

  

LDL-C, mean (SD), mmol/L

2.84

0.86

3.17

1.01

14.378

<  0.001***

Increase (LDL-C ≥ 3.10 mmol/L), n (%)

222

36.3

70

54.7

  

Normal (LDL-C < 3.10 mmol/L), n (%)

390

63.7

58

45.3

  

TG, mean (SD), mmol/L

2.12

0.97

2.25

1.05

1.756

0.185

Increase (TG > 1.69 mmol/L), n (%)

368

60.0

79

61.7

  

Normal (0.56–1.69 mmol/L), n (%)

244

40.0

49

38.3

  
  1. Note: MDD major depressive disorder, HAMD Hamilton depression rating scale, HAMA Hamilton anxiety rating scale, PANSS The Positive and Negative Syndrome Scale, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride. *p <  0.05; **p <  0.01; ***p <  0.001
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BMC Psychiatry

ISSN: 1471-244X

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