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Table 1 Socio-demographics, clinical characteristics and metabolic indictors between patients with and without suicide attempts

From: Potential metabolic monitoring indicators of suicide attempts in first episode and drug naive young patients with major depressive disorder: a cross-sectional study

Variable MDD without suicide attempt (n = 612) MDD with suicide attempt (n = 128) F/X2 P value
Age, mean (SD), y 22.68 4.09 22.98 3.765 0.610 0.435
Course of disease, mean (SD), m 4.58 2.99 5.54 3.85 9.710 0.002**
Gender
 Male, n (%) 236 38.6 51 39.8   
 Female, n (%) 376 61.4 77 60.2   
Cultural degree
 Junior high school education level, n (%) 29 4.8 13 10.2   
 Senior high school education level, n (%) 300 49.0 55 43.0   
 University education level, n (%) 240 39.2 50 39.0   
 Postgraduate education level, n (%) 43 7.0 10 7.8   
Marital status
 Single 384 62.7 86 67.2   
 Married 228 37.3 42 32.8   
HAMD, mean (SD) 29.71 2.84 32.08 2.75 74.600 <  0.001 ***
HAMA, mean (SD) 20.03 3.10 23.20 3.47 105.711 <  0.001 ***
Obvious anxiety (HAMA ≥21), n (%) 270 44.1 102 79.7 740 <  0.001 ***
Psychotic symptoms (PANSS ≥15), n (%) 43 7.02 24 18.75 6.643 0.012*
BMI, mean (SD), kg/m2 24.31 1.87 24.14 2.75 0.694 0.405
SBP, mean (SD), mmHg 111.82 9.19 119.42 12.57 62.909 <  0.001***
DBP, mean (SD), mmHg 72.98 5.81 76.63 7.01 38.651 <  0.001***
FBG, mean (SD), mmol/L 5.32 0.61 5.61 0.70 23.145 <  0.001***
Increase (FBG > 6.10 mmol/L), n (%) 66 10.8 29 22.7   
Normal (3.90–6.10 mmol/L), n (%) 546 89.2 99 77.3   
TC, mean (SD), mmol/L 5.00 1.07 5.80 1.14 57.461 <  0.001***
Increase (TC ≥ 5.17 mmol/L), n (%) 255 41.6 83 64.8   
Normal (TC < 5.17 mmol/L), n (%) 357 58.4 45 35.2   
HDL-C, mean (SD), mmol/L 1.25 0.28 1.12 0.31 20.920 <  0.001***
Decrease (HDL-C < 1.04 mmol/L), n (%) 147 24.0 55 43.0   
Normal (1.04–2.07 mmol/L), n (%) 465 76.0 73 57.0   
LDL-C, mean (SD), mmol/L 2.84 0.86 3.17 1.01 14.378 <  0.001***
Increase (LDL-C ≥ 3.10 mmol/L), n (%) 222 36.3 70 54.7   
Normal (LDL-C < 3.10 mmol/L), n (%) 390 63.7 58 45.3   
TG, mean (SD), mmol/L 2.12 0.97 2.25 1.05 1.756 0.185
Increase (TG > 1.69 mmol/L), n (%) 368 60.0 79 61.7   
Normal (0.56–1.69 mmol/L), n (%) 244 40.0 49 38.3   
  1. Note: MDD major depressive disorder, HAMD Hamilton depression rating scale, HAMA Hamilton anxiety rating scale, PANSS The Positive and Negative Syndrome Scale, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride. *p <  0.05; **p <  0.01; ***p <  0.001