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Table 1 Demographic characteristics of MDD patients and baseline HDRS-17 scores: comparison between responder and non-responder groups

From: Influence of genetic polymorphisms in homocysteine and lipid metabolism systems on antidepressant drug response

Demographic characteristics

Responder

(n = 205)

Non-responder

(n = 76)

t / χ2

P

Gender (male/female)

81/124

35/41

0.987

0.324

Age (years)

38.99 ± 12.93

36.18 ± 13.36

1.599

0.111

Education (years)

11.27 ± 3.84

12.20 ± 3.82

−1.800

0.073

Family history of mood disorder (yes/no)

29 (14.15%)

15 (19.74%)

−1.031

0.305

Baseline HDRS-17 score

28.18 ± 5.68

26.01 ± 5.32

2.891

0.004

Number of episodes

2.01 ± 1.57

2.33 ± 2.03

−1.394

0.164

Antidepressant (SSRI/SNRI)

114/91

50/26

1.569

0.119

  1. Abbreviations: HDRS-17 17-item Hamilton Depression Rating Scale, SNRI serotonin norepinephrine reuptake inhibitor, SSRI selective serotonin reuptake inhibitor