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Table 2 Comparison between the MAO group and the MHNW group for patients with schizophrenia

From: Schizophrenia patients with a metabolically abnormal obese phenotype have milder negative symptoms

 

Total (n = 83)

MAO (n = 52)

MHNW (n = 31)

  

N

%

N

%

N

%

χ2

P

Female

34

41.0

28

53.8

6

19.4

9.55

0.002

Married

21

25.3

15

28.8

6

19.4

2.36

0.500

Current smokers

24

28.9

13

25.0

11

35.5

2.06

0.356

Insulin resistance

32

40.0

29

56.9

3

10.3

16.67

< 0.001

Food intake

 I

24

29.6

13

26.0

11

35.5

0.825

0.364

 II

57

70.4

37

74.0

20

64.5

  

Antipsychotics

 Clozapine

36

43.4

24

46.2

12

38.7

0.438

0.508

 Olanzapine

16

19.3

10

19.2

6

19.4

0.01

0.989

 Risperidone

28

33.7

16

30.8

12

38.7

0.55

0.459

 Aripiprazole

15

18.1

8

15.4

7

22.6

0.68

0.410

 

Mean

SD

Mean

SD

Mean

SD

Z/t

P

Age (years)

43.36

12.44

43.40

12.40

43.29

12.73

0.04

0.968

Education (years)

7.63

4.01

8.42

4.04

6.29

3.65

−2.80

0.005

Age of onset (years)

26.33

8.12

26.79

9.73

25.55

8.31

0.671

0.504

Duration of illness (years)

16.94

10.18

16.42

9.73

17.81

10.99

−0.39

0.695

hospitalization days

109.47

103.18

120.62

125.02

92.73

54.50

−0.731

0.465

Chlorpromazine equivalents (mg/day)

457.38

277.47

404.47

241.49

546.13

313.54

−2.31

0.024

BMI (kg/m2)

26.86

4.72

30.21

1.74

21.23

1.82

22.35

< 0.001

Glucose (mmol/l)

5.33

1.35

5.57

1.63

4.93

0.44

−1.78

0.075

Cholesterol (mmol/l)

4.81

1.17

5.11

1.24

4.32

0.86

3.12

0.003

Triglycerides (mmol/l)

2.37

1.77

3.13

1.87

1.13

0.35

−7.18

< 0.001

HDL _C (mmol/l)

1.07

0.25

0.95

0.19

1.28

0.19

−7.59

< 0.001

LDL_C (mmol/l)

2.45

0.58

2.56

0.55

2.28

0.60

2.13

0.036

Glucagon (pg/ml)

28.29

20.26

34.75

20.86

17.46

13.73

4.11

< 0.001

C-peptide (ng/ml)

3.09

1.37

3.66

1.36

2.08

0.60

5.95

< 0.001

Insulin (mU/L)

12.16

12.55

15.74

14.33

5.74

3.07

−5.68

< 0.001

HOMA-IR

3.24

5.20

4.36

6.24

1.26

0.70

−5.73

< 0.001

PANSS

 Positive factor

9.95

4.58

9.96

4.54

9.94

4.71

0.025

0.980

 Negative factor

18.39

7.42

15.94

6.89

22.48

6.49

−4.28

< 0.001

 Cognitive factor

8.98

2.96

8.44

3.22

9.87

2.25

−2.17

0.033

 Depressive factor

6.88

2.87

7.00

3.02

6.68

2.65

0.49

0.624

 Excited factor

7.71

3.59

7.67

3.78

7.77

3.30

−0.13

0.899

 PANSS total

78.65

23.84

74.50

25.46

85.61

19.30

−2.10

0.039

  1. MAO Metabolically abnormal obese, MHNW Metabolically healthy normal-weight, BMI Body mass index, HDL_C High-density lipoprotein cholesterol, LDL_C Low-density lipoprotein cholesterol, insulin resistance HOMA-IR ≥ 2.5, HOMA-IR Homeostasis model assessment of insulin resistance, PANSS Positive and negative syndrome scale