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Table 3 Mean costs and mean effects per group in the complete sample and subgroups over the course of twelve months (€ 2012)

From: Cost-effectiveness of guideline-based stepped and collaborative care versus treatment as usual for patients with depression – a cluster-randomized trial

  Total sample (n = 737) Subgroup: Mild depression (n = 93)
(PHQ-9: 5–9)
Subgroup: Moderate depression (n = 232)
(PHQ-9: 10–14)
Subgroup: Moderately severe depression (n = 271)
(PHQ-9: 15–19)
Subgroup: Severe depression (n = 141)
(PHQ-9: 20–27)
  Intervention group (n = 569) Control group
(n = 168)
Intervention group (n = 63) Control group
(n = 30)
Intervention group (n = 175) Control group
(n = 57)
Intervention group (n = 221) Control group
(n = 50)
Intervention group (n = 110) Control group
(n = 31)
  Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD)
Total costs (€) 23,920 (28,421) 21,430 (23,506) 20,228 (27,672) 13,798 (17,119) 17,729 (22,325) 21,443 (24,051) 24,647 (29,292) 24,400 (24,964) 34,425 (32,533) 23,999 (24,456)
Healthcare costs (€) 8955 (16,990) 8724 (14,569) 8576 (18,104) 5359 (8910) 6083 (13,080) 8513 (13,170) 9346 (17,920) 8859 (15,794) 12,953 (19,088) 12,149 (18,559)
 Inpatient services (€) 6140 (15,713) 6129 (13,180) 5583 (15,738) 3507 (8362) 3612 (12,111) 6030 (11,936) 6361 (16,423) 6035 (14,805) 10,037 (18,413) 9002 (15,959)
  Psychiatric hospital (€) 926 (4927) 1807 (6313) 1419 (5639) 542 (3845) 605 (5660) 1219 (5605) 837 (4338) 2531 (8794) 1332 (4575) 2943 (7847)
 Outpatient physician services (€) 1867 (1591) 1571 (1543) 1542 (1553) 1022 (962) 1663 (1446) 1571 (1644) 2015 (1706) 1584 (1367) 2078 (1540) 2082 (1909)
  Psychiatrist (€) 199 (372) 110 (250) 178 (347) 61 (192) 160 (346) 108 (260) 217 (394) 142 (272) 239 (376) 110 (236)
  Psychotherapist (€) 950 (1174) 761 (1257) 638 (1028) 261 (601) 894 (1151) 793 (1398) 1025 (1222) 801 (1142) 1069 (1164) 1122 (1502)
 Outpatient non-physician services (€) 240 (524) 267 (528) 248 (578) 248 (399) 153 (357) 294 (597) 289 (624) 231 (455) 274 (482) 291 (622)
 Drugs (€) 463 (1993) 700 (2172) 887 (3721) 570 (1012) 417 (2024) 517 (781) 446 (1701) 956 (3375) 328 (547) 750 (2297)
 Ambulatory care (€) 26 (210) 47 (300) 27 (197) 4 (71) 41 (290) 87 (464) 15 (154) 41 (198) 24 (157) 23 (155)
 Intervention in step 2 (€) 196 (279) 0 (0) 253 (309) 0 (0) 179 (265) 0 (0) 197 (285) 0 (0) 188 (265) 0 (0)
Costs of familiy support
 Informal care (€) 623 (2952) 607 (2423) 627 (3182) 115 (1101) 257 (1700) 627 (1951) 844 (3569) 867 (3114) 760 (2978) 626 (2802)
Productivity losses (€) 14,342 (17,105) 12,099 (15,161) 11,026 (15,329) 8324 (12,141) 11,389 (14,567) 12,303 (15,551) 14,457 (16,708) 14,674 (17,023) 20,712 (20,609) 11,224 (13,383)
QALY (EQ-5D: UK-Tarif) 0.65 (0.23) 0.61 (0.23) 0.68 (0.21) 0.67 (0.24) 0.71 (0.18) 0,64 (0.19) 0.63 (0.24) 0.61 (0.23) 0.58 0,50 (0,26)