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Table 3 Poisson regression: Prevalence of and factors associated with adherence to antiretroviral therapy among people living with HIV/AIDS in Felege-Hiwot Referral Hospital, Northwest Ethiopia, (N = 353)

From: Major depressive disorder and its association with adherence to antiretroviral therapy and quality of life: cross-sectional survey of people living with HIV/AIDS in Northwest Ethiopia

Sociodemographic and clinical factors Prevalence of high adherence, % (n) Unadjusted Poisson regression Adjusted Poisson regression
Risk ratio 95%CI P value Risk ratio 95%CI P value
Age in years a 18–29 79.2 (38) Reference      
30–39 82.4 (122) 1.04 0.73, 1.47 0.845    
40–49 81.1 (86) 1.02 0.71, 1.47 0.920    
50+ 84.4 (38) 1.06 0.69, 1.64 0.792    
Gender a Male 83.3 (90) 1.03 0.80, 1.32 0.840    
Female 81.0 (196) Reference      
Marital status a Single 76.0 (38) Reference      
Married/ in relationship 85.7 (144) 1.13 0.79, 1.61 0.510    
Divorced/widowed 79.3 (107) 1.04 0.72, 1.51 0.824    
Educational status a Illiterate 77.9 (88) Reference      
Primary education 79.5 (89) 1.02 0.76, 1.37 0.893    
Secondary education 85.4 (70) 1.09 0.80, 1.50 0.566    
Tertiary education 91.3 (42) 1.17 0.81, 1.69 0.396    
Employment a Public employed 91.9 (68) 1.21 0.88, 1.66 0.245    
Self employed 81.3 (135) 1.07 0.82, 1.40 0.631    
Unemployed 75.9 (85) Reference      
Perceived social support a High support 82.8 (164) 1.14 0.74, 1.75 0.552    
Moderate support 82.8 (101) 1.14 0.73, 1.78 0.568    
Low support 69.2 (18) Reference      
ART regimen a First-line 84.4 (217) 1.13 0.86, 1.47 0.383    
Second-line 75.8 (69) Reference      
Functional disability No 89.6 (189) 1.27 0.99, 1.62 0.052 1.06 0.79, 1.41 0.710
Yes 70.8 (98) Reference    Reference   
Current CD4 count (last 6 months) a < 200 79.2 (19) Reference      
200–349 81.3 (52) 1.08 0.70, 1.68 0.719    
350–499 86.0 (74) 1.15 0.76, 1.73 0.512    
> 500 81.8 (130) 1.09 0.74, 1.60 0.658    
ART treatment duration in years a 1–5 82.3 (51) Reference      
6–10 82.4 (98) 1.05 0.76, 1.45 0.765    
11 and above 83.1 (133) 1.06 0.78, 1.44 0.709    
Major depressive disorder No 91.9 (215) 1.48 1.14, 1.92 0.004 1.43 1.05, 1.96 0.025
Yes 62.2 (74) Reference    Reference   
  1. NOTE: First-line regimen is the use of first choice antiviral drugs and a switch to second-line regimen is recommended when there is treatment failure with first-line treatments. a variables not included in multivariate Poisson regression; ART antiretroviral therapy