Table 4 Linear regression: Association of socio-demographic and clinical factors with overall quality of life among people living with HIV/AIDS in Felege-Hiwot Referral Hospital, Northwest Ethiopia, (N = 391)

Age in years

18–29

3.76 (0.40)

Reference

Reference

Reference

Reference

30–39

3.86 (0.44)

0.27

−0.26, 0.80

0.313

0.07

−0.04, 0.19

0.209

40–49

3.91 (0.43)

0.49

−0.07, 1.05

0.087

0.10

−0.2, 0.23

0.102

50+

3.83 (0.37)

0.18

− 0.48, 0.83

0.601

0.06

−0.08.0.21

0.371

Gender ^a

Male

3.90 (0.39)

0.23

−0.16, 0.61

0.255

Female

3.84 (0.44)

Reference

Reference

Marital status

Single

3.77 (0.45)

−0.08

− 0.65, 0.48

0.770

− 0.04

− 0.16, 0.08

0.530

Married/ in relationship

3.93 (0.39)

0.57

0.18, 0.95

< 0.004

−0.01

− 0.08, 0.08

0.974

Divorced/widowed

3.79 (0.45)

Reference

Reference

Reference

Reference

Educational status

Illiterate

3.67 (0.50)

Reference

Reference

Reference

Reference

Primary education

3.87 (0.37)

0.78

0.35, 1.21

< 0.001

0.13

0.03, 0.22

< 0.008

Secondary education

3.95 (0.35)

1.12

0.65, 1.58

< 0.001

0.20

0.09, 0.31

< 0.001

Tertiary education

4.09 (0.31)

1.69

1.13, 2.25

< 0.001

0.34

0.19, 0.49

< 0.001

Employment status

Public employed

4.01 (0.32)

0.85

0.37, 1.33

0.001

−0.07

−0.19, 0.05

0.274

Self employed

3.83 (0.42)

0.14

−0.27, 0.55

0.499

0.01

−0.08, 0.09

0.886

None employed

3.81 (0.44)

Reference

Reference

Reference

Reference

ART regimen

First-line

3.90 (0.41)

0.59

0.18, 0.99

< 0.005

0.12

0.03, 0.20

< 0.008

Second-line

3.76 (0.45)

Reference

Reference

Reference

Reference

Current CD4 count (last 6 months)

< 200

3.85 (0.45)

Reference

Reference

Reference

Reference

200–349

3.88 (0.37)

0.34

−0.315, 0.99

0.307

−0.01

− 0.14, 0.13

0.937

350–499

3.94 (0.38)

0.58

−0.042, 1.20

0.067

0.06

−0.07, 0.19

0.343

> 500

3.83 (0.43)

0.16

−0.40, 0.72

0.575

0.01

−0.11, 0.13

0.865

Duration of ART treatment in years

1–5

3.83 (0.49)

Reference

Reference

Reference

6–10

3.91 (0.41)

0.35

−0.14, 0.85

0.157

0.12

0.02, 0.22

0.022

11 and above

3.84 (0.41)

0.05

−0.42, 0.52

0.835

−0.01

− 0.11, 0.10

0.931

Perceived social support

Low support

3.38 (0.62)

Reference

Reference

Reference

Reference

Moderate support

3.68 (0.36)

0.90

0.27, 1.54

0.006

0.18

0.04, 0.33

0.014

High support

3.86 (0.42)

2.19

1.59, 2.80

< 0.001

0.43

0.29, 0.57

< 0.001

Functional disability

No

4.01 (0.33)

1.42

1.08, 1.75

< 0.001

0.29

0.21, 0.36

< 0.001

Yes

3.64 (0.47)

Reference

Reference

Reference

Reference