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Table 4 Linear regression: Association of socio-demographic and clinical factors with overall quality of life among people living with HIV/AIDS in Felege-Hiwot Referral Hospital, Northwest Ethiopia, (N = 391)

From: Major depressive disorder and its association with adherence to antiretroviral therapy and quality of life: cross-sectional survey of people living with HIV/AIDS in Northwest Ethiopia

Factors Mean (SD) Unadjusted linear regression Adjusted multivariate linear regression
Coefficient 95%CI P value Coefficient 95%CI P value
Age in years 18–29 3.76 (0.40) Reference Reference   Reference Reference  
30–39 3.86 (0.44) 0.27 −0.26, 0.80 0.313 0.07 −0.04, 0.19 0.209
40–49 3.91 (0.43) 0.49 −0.07, 1.05 0.087 0.10 −0.2, 0.23 0.102
50+ 3.83 (0.37) 0.18 − 0.48, 0.83 0.601 0.06 −0.08.0.21 0.371
Gender a Male 3.90 (0.39) 0.23 −0.16, 0.61 0.255    
Female 3.84 (0.44) Reference Reference     
Marital status Single 3.77 (0.45) −0.08 − 0.65, 0.48 0.770 − 0.04 − 0.16, 0.08 0.530
Married/ in relationship 3.93 (0.39) 0.57 0.18, 0.95 < 0.004 −0.01 − 0.08, 0.08 0.974
Divorced/widowed 3.79 (0.45) Reference Reference   Reference Reference  
Educational status Illiterate 3.67 (0.50) Reference Reference   Reference Reference  
Primary education 3.87 (0.37) 0.78 0.35, 1.21 < 0.001 0.13 0.03, 0.22 < 0.008
Secondary education 3.95 (0.35) 1.12 0.65, 1.58 < 0.001 0.20 0.09, 0.31 < 0.001
Tertiary education 4.09 (0.31) 1.69 1.13, 2.25 < 0.001 0.34 0.19, 0.49 < 0.001
Employment status Public employed 4.01 (0.32) 0.85 0.37, 1.33 0.001 −0.07 −0.19, 0.05 0.274
Self employed 3.83 (0.42) 0.14 −0.27, 0.55 0.499 0.01 −0.08, 0.09 0.886
None employed 3.81 (0.44) Reference Reference   Reference Reference  
ART regimen First-line 3.90 (0.41) 0.59 0.18, 0.99 < 0.005 0.12 0.03, 0.20 < 0.008
Second-line 3.76 (0.45) Reference Reference   Reference Reference  
Current CD4 count (last 6 months) < 200 3.85 (0.45) Reference Reference   Reference Reference  
200–349 3.88 (0.37) 0.34 −0.315, 0.99 0.307 −0.01 − 0.14, 0.13 0.937
350–499 3.94 (0.38) 0.58 −0.042, 1.20 0.067 0.06 −0.07, 0.19 0.343
> 500 3.83 (0.43) 0.16 −0.40, 0.72 0.575 0.01 −0.11, 0.13 0.865
Duration of ART treatment in years 1–5 3.83 (0.49) Reference    Reference Reference  
6–10 3.91 (0.41) 0.35 −0.14, 0.85 0.157 0.12 0.02, 0.22 0.022
11 and above 3.84 (0.41) 0.05 −0.42, 0.52 0.835 −0.01 − 0.11, 0.10 0.931
Perceived social support Low support 3.38 (0.62) Reference Reference   Reference Reference  
Moderate support 3.68 (0.36) 0.90 0.27, 1.54 0.006 0.18 0.04, 0.33 0.014
High support 3.86 (0.42) 2.19 1.59, 2.80 < 0.001 0.43 0.29, 0.57 < 0.001
Functional disability No 4.01 (0.33) 1.42 1.08, 1.75 < 0.001 0.29 0.21, 0.36 < 0.001
Yes 3.64 (0.47) Reference Reference   Reference Reference  
  1. NOTE: First-line regimen is the use of first choice antiviral drugs and a switch to second-line regimen is recommended when there is treatment failure with first-line treatments. a not included in the final model of analysis; ART antiretroviral therapy