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Table 1 Overview on time points of measurement

From: Schema therapy versus cognitive behavioral therapy versus individual supportive therapy for depression in an inpatient and day clinic setting: study protocol of the OPTIMA-RCT

Study week

T0

T1

T2

T3

T4

T5

T6

T7

T8

T9

  

Treatment phase

  

Primary outcome

 BDI

x

x

x

x

x

x

x

x

x

x

Secondary outcomes

 MADRS

x

   

x

  

x

x

x

 M-CIDI

x

      

x

x

x

 WHODAS

x

   

x

  

x

  

 WHOQOL

x

   

x

  

x

  

 Self-reports

x

x

x

x

x

x

x

x

x

x

MOCs and process measures

 Self-reports

x

x

x

x

x

x

x

x

x

x

 Actimetrya

xxx

xxx

xxx

xxx

xxx

xxx

xxx

xxx

  

 Psychophysiology

 

xx

xx

xx

xx

xx

xx

xx

  

 EMA

xxx

xxx

xxx

xxx

xxx

xxx

xxx

xxx

  

Potential predictors

 Neuropsychologya

x

      

x

x

 

 ECGa

x

      

x

  

 Biological parameters

55ml

   

28ml

  

28ml

28ml

28ml

 Neuroimaging

x

      

x

  

 Learning Task

 

x

     

x

  
  1. Note: T0 = baseline measures before treatment start; T1 = first study week; etc.; T8 = six months follow-up; T9 = 24 months follow-up; x = one time point of measurement per week; xx = two time points of measurement per week; xxx = quasi continuous data collection ranging from three times per day (EMA) to every 30 seconds (actimetry). aAssessment domains are obligatory; Secondary outcome self-reports include BSI, WHODAS, and WHO-QOL; For further details on the MOC measures (particularly common factor measures) see Additional file 1: Appendix A.