TY - JOUR AU - Murray, C. J. AU - Vos, T. AU - Lozano, R. AU - Naghavi, M. AU - Flaxman, A. D. AU - Michaud, C. PY - 2012 DA - 2012// TI - Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the global burden of disease study 2010 JO - Lancet. VL - 380 UR - https://doi.org/10.1016/S0140-6736(12)61689-4 DO - 10.1016/S0140-6736(12)61689-4 ID - Murray2012 ER - TY - JOUR AU - Oladeji, B. D. AU - Gureje, O. PY - 2013 DA - 2013// TI - The comorbidity between depression and diabetes JO - Curr Psychiatry Rep VL - 15 UR - https://doi.org/10.1007/s11920-013-0390-3 DO - 10.1007/s11920-013-0390-3 ID - Oladeji2013 ER - TY - JOUR AU - Ning, G. PY - 2013 DA - 2013// TI - The incidence of diabetes in China increased ten times in thirty years JO - Med Health Care VL - 01 ID - Ning2013 ER - TY - JOUR AU - Roy, T. AU - Lloyd, C. E. PY - 2012 DA - 2012// TI - Epidemiology of depression and diabetes: a systematic review JO - J Affect Disord VL - 142 UR - https://doi.org/10.1016/S0165-0327(12)70004-6 DO - 10.1016/S0165-0327(12)70004-6 ID - Roy2012 ER - TY - JOUR AU - Belvederi, M. M. AU - Mamberto, S. AU - Briatore, L. AU - Mazzucchelli, C. AU - Amore, M. AU - Cordera, R. PY - 2017 DA - 2017// TI - The interplay between diabetes, depression and affective temperaments: a structural equation model JO - J Affect Disord VL - 219 UR - https://doi.org/10.1016/j.jad.2017.05.018 DO - 10.1016/j.jad.2017.05.018 ID - Belvederi2017 ER - TY - JOUR AU - Siddiqui, S. PY - 2014 DA - 2014// TI - Depression in type 2 diabetes mellitus—a brief review JO - Diab Metab Syndr VL - 8 UR - https://doi.org/10.1016/j.dsx.2013.06.010 DO - 10.1016/j.dsx.2013.06.010 ID - Siddiqui2014 ER - TY - JOUR AU - Singh, H. AU - Raju, M. S. V. K. AU - Dubey, V. AU - Kurrey, R. AU - Bansal, S. AU - Malik, M. PY - 2014 DA - 2014// TI - A study of sociodemographic clinical and glycemic control factors associated with comorbid depression in type 2 diabetes mellitus JO - Ind Psychiatry J VL - 23 UR - https://doi.org/10.4103/0972-6748.151687 DO - 10.4103/0972-6748.151687 ID - Singh2014 ER - TY - JOUR AU - Das, R. AU - Singh, O. AU - Thakurta, R. G. AU - Khandakar, M. R. AU - Ali, S. N. AU - Mallick, A. K. PY - 2013 DA - 2013// TI - Prevalence of depression in patients with type II diabetes mellitus and its impact on quality of life JO - Indian J Psychol Med VL - 35 UR - https://doi.org/10.4103/0253-7176.119502 DO - 10.4103/0253-7176.119502 ID - Das2013 ER - TY - JOUR AU - Roy, T. AU - Lloyd, C. E. AU - Parvin, M. AU - Mohiuddin, K. G. AU - Rahman, M. PY - 2012 DA - 2012// TI - Prevalence of co-morbid depression in out-patients with type 2 diabetes mellitus in Bangladesh JO - BMC Psychiatry VL - 12 UR - https://doi.org/10.1186/1471-244X-12-123 DO - 10.1186/1471-244X-12-123 ID - Roy2012 ER - TY - JOUR AU - Iype, T. AU - Shaji, S. K. AU - Balakrishnan, A. AU - Charles, D. AU - Varghese, A. A. AU - Antony, T. P. PY - 2019 DA - 2019// TI - Cognition in type 2 diabetes: association with vascular risk factors, complications of diabetes and depression JO - Ann Indian Acad Neurol VL - 12 ID - Iype2019 ER - TY - JOUR AU - Jones, A. G. AU - Hattersley, A. T. PY - 2013 DA - 2013// TI - The clinical utility of C-peptide measurement in the care of patients with diabetes JO - Diabet Med VL - 30 UR - https://doi.org/10.1111/dme.12159 DO - 10.1111/dme.12159 ID - Jones2013 ER - TY - JOUR AU - Tang, Z. Q. AU - Cui, S. W. AU - Zhu, X. H. AU - Wang, C. F. AU - Yin, T. PY - 2012 DA - 2012// TI - The C2/C0 ratio (2 h postprandial over fasting C-peptide ratio) may be predictive index for glucose control after insulin intensive therapy in newly diagnosed type 2 diabetes JO - Chin J Diabetes VL - 20 ID - Tang2012 ER - TY - JOUR AU - Hope, S. V. AU - Knight, B. A. AU - Shields, B. M. AU - Hill, A. V. AU - Choudhary, P. AU - Strain, W. D. PY - 2018 DA - 2018// TI - Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia JO - Diabetologia. VL - 61 UR - https://doi.org/10.1007/s00125-017-4449-2 DO - 10.1007/s00125-017-4449-2 ID - Hope2018 ER - TY - JOUR AU - Yoshida, S. AU - Hirai, M. AU - Suzuki, S. AU - Awata, S. AU - Oka, Y. PY - 2009 DA - 2009// TI - Neuropathy is associated with depression independently of health-related quality of life in Japanese patients with diabetes JO - Psychiatry Clin Neurosci VL - 63 UR - https://doi.org/10.1111/j.1440-1819.2008.01889.x DO - 10.1111/j.1440-1819.2008.01889.x ID - Yoshida2009 ER - TY - JOUR AU - Martins, I. AU - Gomes, S. AU - Costa, R. O. AU - Otvos, L. AU - Oliveira, C. R. AU - Resende, R. PY - 2013 DA - 2013// TI - Leptin and ghrelin prevent hippocampal dysfunction induced by Aβoligomers JO - Neuroscience. VL - 241 UR - https://doi.org/10.1016/j.neuroscience.2013.02.062 DO - 10.1016/j.neuroscience.2013.02.062 ID - Martins2013 ER - TY - JOUR AU - Klok, M. D. AU - Jakobsdottir, S. AU - Drent, M. L. PY - 2007 DA - 2007// TI - The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review JO - Obes Rev VL - 8 UR - https://doi.org/10.1111/j.1467-789X.2006.00270.x DO - 10.1111/j.1467-789X.2006.00270.x ID - Klok2007 ER - TY - JOUR AU - Tschop, M. AU - Smiley, D. L. AU - Heiman, M. L. PY - 2000 DA - 2000// TI - Ghrelin induces adiposity in rodents JO - Nature. VL - 407 UR - https://doi.org/10.1038/35038090 DO - 10.1038/35038090 ID - Tschop2000 ER - TY - JOUR AU - Spencer, S. J. AU - Emmerzaal, T. L. AU - Kozicz, T. AU - Andrews, Z. B. PY - 2015 DA - 2015// TI - Ghrelin’s role in the hypothalamic-pituitary-adrenal Axis stress response: implications for mood disorders JO - Biol Psychiatry VL - 78 UR - https://doi.org/10.1016/j.biopsych.2014.10.021 DO - 10.1016/j.biopsych.2014.10.021 ID - Spencer2015 ER - TY - JOUR AU - Alvarez-Crespo, M. AU - Skibicka, K. P. AU - Farkas, I. AU - Molnár, C. S. AU - Egecioglu, E. AU - Hrabovszky, E. PY - 2012 DA - 2012// TI - The amygdala as a neurobiological target for ghrelin in rats: neuroanatomical, electrophysiological and behavioral evidence JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0046321 DO - 10.1371/journal.pone.0046321 ID - Alvarez-Crespo2012 ER - TY - JOUR AU - Krishnan, V. AU - Nestler, E. J. PY - 2010 DA - 2010// TI - Linking molecules to mood: new insight into the biology of depression JO - Am J Psychiatry VL - 167 UR - https://doi.org/10.1176/appi.ajp.2009.10030434 DO - 10.1176/appi.ajp.2009.10030434 ID - Krishnan2010 ER - TY - JOUR AU - Farr, O. M. AU - Tsoukas, M. A. AU - Mantzoros, C. S. PY - 2015 DA - 2015// TI - Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders JO - Metabolism. VL - 64 UR - https://doi.org/10.1016/j.metabol.2014.07.004 DO - 10.1016/j.metabol.2014.07.004 ID - Farr2015 ER - TY - JOUR AU - Lu, X. Y. PY - 2007 DA - 2007// TI - The leptin hypothesis of depression: a potential link between mood disorders and obesity? JO - Curr Opin Pharmacol VL - 7 UR - https://doi.org/10.1016/j.coph.2007.10.010 DO - 10.1016/j.coph.2007.10.010 ID - Lu2007 ER - TY - JOUR AU - Poretti, M. B. AU - Rask-Andersen, M. AU - Kumar, P. AU - Rubiales de Barioglio, S. AU - Fiol de Cuneo, M. AU - Schiöth, H. B. PY - 2015 DA - 2015// TI - Ghrelin effects expression of several genes associated with depression-like behavior JO - Prog Neuropsychopharmacol Biol Psychiatry VL - 56 UR - https://doi.org/10.1016/j.pnpbp.2014.09.012 DO - 10.1016/j.pnpbp.2014.09.012 ID - Poretti2015 ER - TY - JOUR AU - Barim, A. O. AU - Aydin, S. AU - Colak, R. AU - Dag, E. AU - Deniz, O. AU - Sahin, I. PY - 2009 DA - 2009// TI - Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment JO - Clin Biochem VL - 42 UR - https://doi.org/10.1016/j.clinbiochem.2009.02.020 DO - 10.1016/j.clinbiochem.2009.02.020 ID - Barim2009 ER - TY - JOUR AU - Ozsoy, S. AU - Besirli, A. AU - Abdulrezzak, U. AU - Basturk, M. PY - 2014 DA - 2014// TI - Serum ghrelin and Leptin levels in patients with depression and the effects of treatment JO - Psychiatry Investig VL - 11 UR - https://doi.org/10.4306/pi.2014.11.2.167 DO - 10.4306/pi.2014.11.2.167 ID - Ozsoy2014 ER - TY - JOUR AU - Matsuo, K. AU - Nakano, M. AU - Nakashima, M. AU - Watanuki, T. AU - Egashira, K. AU - Matsubara, T. PY - 2012 DA - 2012// TI - Neural correlates of plasma acylated ghrelin level in individuals with major depressive disorder JO - Brain Res VL - 1473 UR - https://doi.org/10.1016/j.brainres.2012.07.027 DO - 10.1016/j.brainres.2012.07.027 ID - Matsuo2012 ER - TY - JOUR AU - Poher, A. L. AU - Tschöp, M. H. AU - Müller, T. D. PY - 2018 DA - 2018// TI - Ghrelin regulation of glucose metabolism JO - Peptides. VL - 100 UR - https://doi.org/10.1016/j.peptides.2017.12.015 DO - 10.1016/j.peptides.2017.12.015 ID - Poher2018 ER - TY - JOUR AU - Morris, A. A. AU - Ahmed, Y. AU - Stoyanova, N. AU - Hooper, W. C. AU - Staerke, C. AU - Gibbons, G. PY - 2012 DA - 2012// TI - The association between depression and Leptin is mediated by adiposity JO - Psychosom Med VL - 74 UR - https://doi.org/10.1097/PSY.0b013e31824f5de0 DO - 10.1097/PSY.0b013e31824f5de0 ID - Morris2012 ER - TY - JOUR AU - Milaneschi, Y. AU - Simonsick, E. M. AU - Vogelzangs, N. AU - Strotmeyer, E. S. AU - Yaffe, K. AU - Harris, T. B. PY - 2012 DA - 2012// TI - Leptin, abdominal obesity, and onset of depression in older men and women JO - J Clin Psychiatry VL - 73 UR - https://doi.org/10.4088/JCP.11m07552 DO - 10.4088/JCP.11m07552 ID - Milaneschi2012 ER - TY - JOUR AU - Milaneschi, Y. AU - Sutin, A. R. AU - Terracciano, A. AU - Canepa, M. AU - Gravenstein, K. S. AU - Egan, J. M. PY - 2014 DA - 2014// TI - The association between leptin and depressive symptoms is modulated by abdominal adiposity JO - Psychoneuroendocrinology. VL - 42 UR - https://doi.org/10.1016/j.psyneuen.2013.12.015 DO - 10.1016/j.psyneuen.2013.12.015 ID - Milaneschi2014 ER - TY - JOUR AU - Lawson, E. A. AU - Miller, K. K. AU - Blum, J. I. AU - Meenaghan, E. AU - Misra, M. AU - Eddy, K. T. PY - 2012 DA - 2012// TI - Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fat JO - Clin Endocrinol VL - 76 UR - https://doi.org/10.1111/j.1365-2265.2011.04182.x DO - 10.1111/j.1365-2265.2011.04182.x ID - Lawson2012 ER - TY - JOUR AU - Zarouna, S. AU - Wozniak, G. AU - Papachristou, A. I. PY - 2015 DA - 2015// TI - Mood disorders: a potential link between ghrelin and leptin on human body? JO - World J Exp Med VL - 5 UR - https://doi.org/10.5493/wjem.v5.i2.103 DO - 10.5493/wjem.v5.i2.103 ID - Zarouna2015 ER - TY - JOUR AU - Pruessner, J. C. AU - Hellhammer, D. H. AU - Kirschbaum, C. PY - 1999 DA - 1999// TI - Burnout, perceived stress, and cortisol responses to awakening JO - Psychosom Med VL - 61 UR - https://doi.org/10.1097/00006842-199903000-00012 DO - 10.1097/00006842-199903000-00012 ID - Pruessner1999 ER - TY - JOUR AU - Herane-Vives, A. AU - Fischer, S. AU - Angel, V. AU - Wise, T. AU - Cheung, E. AU - Chua, K. C. PY - 2018 DA - 2018// TI - Elevated fingernail cortisol levels in major depressive episodes JO - Psychoneuroendocrinology. VL - 88 UR - https://doi.org/10.1016/j.psyneuen.2017.10.026 DO - 10.1016/j.psyneuen.2017.10.026 ID - Herane-Vives2018 ER - TY - JOUR AU - Lecrubier, Y. AU - Sheehan, D. V. AU - Weiller, E. AU - Amorim, P. AU - Bonora, I. AU - Sheehan, K. H. PY - 1997 DA - 1997// TI - The MINI international neuropsychiatric interview (MINI). A short diagnostic structured interview: reliability and validity according to the CIDI. Eur JO - Psychiatry. VL - 12 ID - Lecrubier1997 ER - TY - JOUR AU - Kroenke, K. AU - Spitzer, R. L. PY - 2002 DA - 2002// TI - The PHQ-9: a new depression and diagnostic severity measure JO - Psychiatr Ann VL - 32 UR - https://doi.org/10.3928/0048-5713-20020901-06 DO - 10.3928/0048-5713-20020901-06 ID - Kroenke2002 ER - TY - JOUR AU - Kroenke, K. AU - Spitzer, R. L. AU - Williams, J. B. W. PY - 2001 DA - 2001// TI - The PHQ-9: validity of a brief depression severity measure JO - J Gen Intern Med VL - 16 UR - https://doi.org/10.1046/j.1525-1497.2001.016009606.x DO - 10.1046/j.1525-1497.2001.016009606.x ID - Kroenke2001 ER - TY - JOUR AU - Radloff, S. L. PY - 1977 DA - 1977// TI - The CES-D scale: a self-report depression scale for research in the general population JO - Appl Psychol Dev VL - 1 ID - Radloff1977 ER - TY - JOUR AU - Manea, L. AU - Gilbody, S. AU - McMillan, D. PY - 2012 DA - 2012// TI - Optimal cut-off scores for diagnosing depression with the patient health questionnaire (PHQ-9): a meta-analysis JO - CMAJ. VL - 184 UR - https://doi.org/10.1503/cmaj.110829 DO - 10.1503/cmaj.110829 ID - Manea2012 ER - TY - JOUR AU - Zhang, Y. AU - Ting, R. AU - Lam, M. AU - Lam, J. AU - Nan, H. AU - Yeung, R. PY - 2013 DA - 2013// TI - Measuring depressive symptoms using the patient health Questionnaire-9 in Hong Kong Chinese subjects with type 2 diabetes JO - J Affect Disord VL - 151 UR - https://doi.org/10.1016/j.jad.2013.07.014 DO - 10.1016/j.jad.2013.07.014 ID - Zhang2013 ER - TY - BOOK PY - 2013 DA - 2013// TI - Diagnostic and Statistical Manual of Mental Disorders: DSM-5 PB - Am J Psychiatry CY - Washington UR - https://doi.org/10.1176/appi.books.9780890425596 DO - 10.1176/appi.books.9780890425596 ID - ref41 ER - TY - JOUR AU - Sang, Y. M. AU - Wang, L. J. AU - Mao, H. X. AU - Lou, X. Y. AU - Zhu, Y. J. PY - 2018 DA - 2018// TI - The association of short-term memory and cognitive impairment with ghrelin, leptin, and cortisol levels in non-diabetic and diabetic elderly individuals JO - Acta Diabetol VL - 55 UR - https://doi.org/10.1007/s00592-018-1111-5 DO - 10.1007/s00592-018-1111-5 ID - Sang2018 ER - TY - JOUR AU - Arend, M. G. AU - Shafer, T. PY - 2019 DA - 2019// TI - Statistical power in two-level models: a tutorial based onmonte carlo simulation JO - Psychol Methods VL - 24 UR - https://doi.org/10.1037/met0000195 DO - 10.1037/met0000195 ID - Arend2019 ER - TY - JOUR AU - Zheng, H. M. AU - Wen, Z. L. AU - Wu, Y. PY - 2011 DA - 2011// TI - Selection and analysis of common effect size in psychology JO - Progress Psychol Sci VL - 19 ID - Zheng2011 ER - TY - JOUR AU - Rao, U. PY - 2013 DA - 2013// TI - Biomarkers in pediatric depression JO - Depress Anxiety VL - 30 UR - https://doi.org/10.1002/da.22171 DO - 10.1002/da.22171 ID - Rao2013 ER - TY - JOUR AU - Paslakis, G. AU - Westphal, S. AU - Hamann, B. AU - Gilles, M. AU - Lederbogen, F. AU - Deuschle, M. PY - 2014 DA - 2014// TI - Unstimulated and glucose-stimulated ghrelin in depressed patients and controls JO - J Psychopharmacol VL - 28 UR - https://doi.org/10.1177/0269881114527655 DO - 10.1177/0269881114527655 ID - Paslakis2014 ER - TY - JOUR AU - Stoyanova, I. I. PY - 2014 DA - 2014// TI - Ghrelin: A link between ageing, metabolism and neurodegenerative disorders JO - Neurobiol Dis VL - 72 UR - https://doi.org/10.1016/j.nbd.2014.08.026 DO - 10.1016/j.nbd.2014.08.026 ID - Stoyanova2014 ER - TY - JOUR AU - Roca-Chiapas, J. M. AU - Hernández-González, M. AU - Candelario, M. AU - Villafaña Mde, L. AU - Hernández, E. AU - Solorio, S. PY - 2013 DA - 2013// TI - Association between depression and higher glucose levels in middle-aged Mexican patients with diabetes JO - Rev Investig Clin VL - 65 ID - Roca-Chiapas2013 ER - TY - JOUR AU - Lustman, P. J. AU - Clouse, R. E. PY - 2005 DA - 2005// TI - Depression in diabetic patients: the relationship between mood and glycemic control JO - J Diabetes Complicat VL - 19 ID - Lustman2005 ER - TY - JOUR AU - Saisho, Y. PY - 2014 DA - 2014// TI - Importance of Beta cell function for the treatment of type 2 diabetes JO - J Clin Med VL - 3 UR - https://doi.org/10.3390/jcm3030923 DO - 10.3390/jcm3030923 ID - Saisho2014 ER - TY - JOUR AU - Gecici, O. AU - Kuloglu, M. AU - Atmaca, M. AU - Tezcan, A. E. AU - Tunckol, H. AU - Emül, H. M. PY - 2005 DA - 2005// TI - High serum leptin levels in depressive disorders with atypical features JO - Psychiatry Clin Neurosci VL - 59 UR - https://doi.org/10.1111/j.1440-1819.2005.01445.x DO - 10.1111/j.1440-1819.2005.01445.x ID - Gecici2005 ER - TY - JOUR AU - Kraus, T. AU - Haack, M. AU - Schuld, A. AU - Hinze-Selch, D. AU - Pollmacher, T. PY - 2001 DA - 2001// TI - Low Leptin levels but Norma body mass indices in patients with depression or schizophrenia JO - Neuroendocrinology. VL - 73 UR - https://doi.org/10.1159/000054641 DO - 10.1159/000054641 ID - Kraus2001 ER - TY - JOUR AU - Deuschle, M. AU - Blum, W. F. AU - Englaro, P. AU - Schweiger, U. AU - Weber, B. AU - Pflaum, C. D. PY - 1996 DA - 1996// TI - Plasma Leptin in depressed patients and healthy controls JO - Horm Metab Res VL - 28 UR - https://doi.org/10.1055/s-2007-979885 DO - 10.1055/s-2007-979885 ID - Deuschle1996 ER - TY - JOUR AU - Nanayakkara, N. AU - Pease, A. AU - Ranasinha, S. AU - Wischer, N. AU - Andrikopoulos, S. AU - Speight, J. PY - 2018 DA - 2018// TI - Depression and diabetes distress in adults with type 2 diabetes: results from the Australian National Diabetes Audit (ANDA) 2016 JO - Sci Rep VL - 8 UR - https://doi.org/10.1038/s41598-018-26138-5 DO - 10.1038/s41598-018-26138-5 ID - Nanayakkara2018 ER - TY - JOUR AU - Salinero-Fort, M. A. AU - Gómez-Campelo, P. AU - San Andrés-Rebollo, F. J. AU - Cárdenas-Valladolid, J. AU - Abánades-Herranz, J. C. AU - Carrillo de Santa Pau, E. PY - 2018 DA - 2018// TI - Prevalence of depression in patients with type 2 diabetes mellitus in Spain (the DIADEMA Study): results from the MADIABETES cohort JO - BMJ Open VL - 8 UR - https://doi.org/10.1136/bmjopen-2017-020768 DO - 10.1136/bmjopen-2017-020768 ID - Salinero-Fort2018 ER - TY - JOUR AU - Balardin, J. B. AU - Vedana, G. AU - Luz, C. AU - Bromberg, E. PY - 2011 DA - 2011// TI - Subjective mild depressive symptoms are associated with abnormal diurnal cycle of salivary cortisol in older adults JO - J Geriatr Psychiatry Neurol VL - 24 UR - https://doi.org/10.1177/0891988710373599 DO - 10.1177/0891988710373599 ID - Balardin2011 ER - TY - JOUR AU - Santen, A. AU - Vreeburg, S. A. AU - Does, A. J. AU - Spinhoven, P. AU - Zitman, F. G. AU - Penninx, B. W. PY - 2011 DA - 2011// TI - Psychological traits and the cortisol awakening response: results from the Netherlands study of depression and anxiety JO - Psychoneuroendocrinology. VL - 36 UR - https://doi.org/10.1016/j.psyneuen.2010.07.014 DO - 10.1016/j.psyneuen.2010.07.014 ID - Santen2011 ER - TY - JOUR AU - Kathol, R. G. AU - Jaeckel, R. S. AU - Lopez, J. F. AU - Meller, W. H. PY - 1989 DA - 1989// TI - Pathophysiology of HPA axis abnormalities in patients with major depression: an update JO - Am J Psychiatry VL - 146 UR - https://doi.org/10.1176/ajp.146.3.311 DO - 10.1176/ajp.146.3.311 ID - Kathol1989 ER - TY - JOUR AU - Chen, P. C. AU - Chan, Y. T. AU - Chen, H. F. AU - Ko, M. C. AU - Li, C. Y. PY - 2013 DA - 2013// TI - Population-based cohort analyses of the bidirectional relationship between type 2 diabetes and depression JO - Diabetes Care VL - 36 UR - https://doi.org/10.2337/dc12-0473 DO - 10.2337/dc12-0473 ID - Chen2013 ER -