Functional polymorphisms and transcriptional analysis in the 5′ region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders

Table 4 Information for studied SNPs in HaploReg and Regulome DB

Variant	Promoter/enhancer histone marks	Regulatory motifs altered
rs4140535	12_EnhBiv	5 altered motifs BATF_disc3, GATA_disc3, STAT_known11 etc.
rs1778258	12_EnhBiv, 2_PromU,23_PromBiv	CTCF,Rad21,TR4
rs17273700	12_EnhBiv, 2_PromU,23_PromBiv	7 altered motifs Ahr::Arnt::HIF, BHLHE40_disc2, HEY1_disc2 etc.
rs1228814	12_EnhBiv, 2_PromU,23_PromBiv	8 altered motifs CCNT2_disc2, Ets_disc1, PLAG1 etc.
rs11568817	3_PromD1, 12_EnhBiv, 2_PromU,23_PromBiv
rs130058	3_PromD1, 12_EnhBiv, 2_PromU,23_PromBiv	9 altered motifs GCNF, Nr2f2, RXRA_known1 etc.

ISSN: 1471-244X