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Table 5 Correlates of Neurocognitive and Educational Outcomes in Survivors of Hypoxic-Ischemic Encephalopathy

From: Long-term neurocognitive and educational outcomes of neonatal insults in Kilifi, Kenya

 

Nonverbal intelligence

Planning and problem

Working memory

Visual attention

Syntax

Pragmatics

Word finding

Memory

Perceptual motor

Mathematical skills

Reading skills

Risk factors

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

Step 1 Child factors

 Child’s age in years

0.14(− 0.34–0.91)

0.17(− 0.01–0.18)

0.38**(0.61–2.70)

0.28*(0.07–0.58)

0.25*(− 0.13–1.74)

–

0.18 (− 0.21–1.40)

0.13(− 1.72–5.53)

0.37**(0.16–0.65)

0.39**(1.73–4.54)

0.35**(4.03–11.61)

 Child’s female sex

–

–

–

–

–

–

–

–

–

–

–

 Stunted growth

− 0.16* (−4.04- -0.21)

–

− 0.20* (−8.02- -0.49)

− 0.20* (− 2.01 - -0.16)

−0.29** (−8.17- -2.43)

− 0.15 (−9.19–1.18)

−0.30** (−7.63- -1.88)

−0.31** (− 33.70- -8.39)

−0.08 (− 1.31–0.49)

−0.24** (− 14.52- -4.22)

−0.24** (− 39.83- -11.86)

 Years of Education

0.56** (1.19–2.45)

–

− 0.08 (− 0.87–1.67)

0.35** (− 0.18–0.79)

0.35** (0.66–2.57)

0.17 (0.20–2.46)

0.18 (−0.25–1.68)

0.28* (0.54–9.11)

0.25*(0.04–0.63)

0.39**(2.00–5.41)

0.42**(6.37–15.71)

Step 2 Parental factors

 Education level

–

0.17 (− 0.05–0.78)

–

–

–

–

− 0.08 (− 3.76–1.55)

–

–

–

–

 Marital status

–

–

–

–

− 0.12 (− 5.82–0.92)

–

− 0.09 (− 5.08–1.81)

–

–

–

–

 Family environment

−0.03 (− 0.25–0.38)

–

− 0.06 (− 0.84–0.40)

–

–

–

–

–

–

−0.02 (− 0.99–0.71 2.16)

−0.01 (− 2.49–2.09)

 Mental health

–

–

–

–

–

− 0.12 (− 0.82–0.21)

− 0.19* (− 0.60- -0.01)

–

0.02 (− 0.08–0.10)

–

–

Step 3 Obstetric factors

 Abnormal pregnancy

–

–

–

–

–

–

–

–

0.06 (− 0.57–1.10)

–

0.00 (− 12.70–12.65)

 Place of birth

–

–

–

–

–

–

–

0.06 (− 10.61–20.34)

–

–

–

 Abnormal delivery

–

–

–

–

− 0.16* (− 5.47- -0.12)

–

–

− 0.05 (− 16.22–0.942)

–

–

–

 Delayed crying

–

–

0.07 (−2.31–5.17)

–

–

–

0.06 (− 2.07–3.86)

0.19 (− 0.34–25.69)

–

–

–

 Breast Feeding problems

–

–

–

− 0.13 (− 1.46–0.19)

–

–

–

–

–

–

–

 Febrile seizures

–

–

–

–

− 0.16 (− 6.20- -0.18)

− 0.13 (− 9.15–1.94)

–

− 0.17 (− 26.31–1.47)

–

–

–

 Hospital admission

−0.09 (− 5.01–1.12)

–

–

–

–

–

− 0.01 (− 4.99–4.42)

–

−0.19* (− 3.08- -0.22)

–

− 0.05 (− 30.23–14.31)

 Medical problems

–

–

–

–

–

–

–

–

–

–

–

 Neurological problems

−0.03 (− 2.28–1.44)

–

− 0.14 (− 6.56–0.96)

–

− 0.14 (− 5.33–0.44)

− 0.21* (− 10.48- -0.30)

−0.20* (− 5.98- -0.10)

−0.00 (− 13.30–12.93)

−0.01 (− 0.84–0.90)

−0.01 (− 5.43–4.55)

−0.09 (− 1.38–0.17)

 R2 (P)

0.50 (0.000)

0.25 (0.036)

0.30 (0.000)

0.39 (0.000)

0.48 (0.000)

0.17 (0.005)

0.34 (0.000)

0.34 (0.000)

0.40 (0.00)

0.58 (0.000)

0.61 (0.000)

  1. Note: * p < 0.05; ** p < 0.001; Dash line (−)- the variable was not carried forward to the multivariate analysis