Fig. 1

Gastrointestinal symptoms in controls and patients: Symptoms are measured by total Gastrointestinal Symptoms Rating Scale for Irritable Bowel Syndrome (GSRS-IBS) score. Patients are grouped according to gender, medication state and diagnosis (current depressive episode, any anxiety disorder, or both). Abbreviations: M = men, W = women, Med + = patients with psychotropic medication, Med- = patients without psychotropic medication, D = Current depressive episode, A = Any anxiety disorder, D + A = Current depressive episode and Any anxiety disorder; *** p < 0.001