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Table 1 Main measurement of the MiMiCS-FRAIL cohort

From: Design and protocol of the multimorbidity and mental health cohort study in frailty and aging (MiMiCS-FRAIL): unraveling the clinical and molecular associations between frailty, somatic disease burden and late life depression

Measurement

Baseline

Annually

- Number of chronic diseases (multimorbidity)

x

x

- Number of geriatric syndromes

x

x

- Charlson Comorbidity Index

x

x

- FRAIL questionnaire (self-report Brazilian version)

x

x

- Physical frailty phenotype

x

x

- 36-item Frailty Index

x

x

- Structured Clinical Interview for DSM-5 (section on mood disorders)

x

x

- Patient Health Questionnaire 9-item version

x

x

- Circulating inflammatory and anti-inflammatory cytokines

x

 

- Phenotype of major circulating leukocytes subpopulations

x

 

- Immuno-metabolic-paired miRome analyses

x

 

- Covariates

x

x