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Table 1 Characteristics of participants with and without epileptiform discharges or other sharp activity

From: Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study

 

ED/SA+

(n = 12)

ED/SA-

(n = 74)

p-value

Age

  

0.29

 mean ± SD

35 ± 14

38 ± 12

 

 median (IQR)

32 (9.3)

38 (20)

 

Women, n (%)

8 (67)

40 (54)

0.62§

Years of educationa

  

0.23

 mean ± SD

5.8 ± 3.1

4.7 ± 3.3

 

 median (IQR)

6.0 (3.0)

4.0 (4.0)

 

Family history, n (%)

 Schizophreniab

0 (0)

5 (7.1)

1.0

 Bipolar disorderc

3 (25)

13 (18)

0.69

 Depressiond

5 (42)

39 (53)

0.66§

Medical history, n (%)

 Migrainee

3 (25)

11 (15)

0.41

 Traumatic brain injurye

1 (8.3)

11 (15)

1.0

 Epileptic seizures

0 (0)

3 (4.1)

1.0

Pharmacological treatm., n (%)f

 Lithium

0 (0)

2 (2.7)

1.0

 Anticonvulsants

8 (73)

62 (84)

0.40

 Antipsychotics

4 (36)

29 (39)

1.0

 Antidepressants

5 (45)

34 (46)

1.0§

 Anxiolytics/hypnotics

3 (27)

24 (32)

1.0

 None

1 (9.1)

2 (2.7)

0.34

Psychiatric comorbidity, n (%)

 Alcohol harmful use or dependence

0 (0)

10 (14)

0.34

 Substances harmful use or dependence

0 (0)

4 (5.4)

1.0

 Agoraphobia

0 (0)

3 (4.1)

1.0

 Social phobia

1 (8.3)

8 (11)

1.0

 Specific phobia

1 (8.3)

0 (0)

0.14

 Panic disorder

3 (25)

12 (16)

0.43

 Obsessive-compulsive disorder

1 (8.3)

1 (1.4)

0.26

 Attention deficit hyperactivity disorder g

0 (0)

1 (5.9)

1.0

Symptom burden

 IDS-C30 scored

  mean ± SD

23 ± 13

25 ± 10

0.49

  median (IQR)

25 (12)

25 (17)

 

 YMRS score

  

0.77

  mean ± SD

1.8 (2.3)

1 (2.5)

 

  median (IQR)

2.3 (3.0)

0.5 (4.0)

 
  1. Abbreviations: ED epileptiform discharges, SA other sharp activity, IDS-C30 Inventory of Depressive Symptoms Clinician Rated, IQR interquartile range, SD standard deviation, YMRS Young Mania Rating Scale. Missing data: a 1 in ED/SA- group, b 4 in ED/SA- group, c 2 in ED/SA- group, d 1 in ED/SA- group, e 1 in ED/SA- group, f 1 in ED/SA+ group, g 7 in ED/SA+ and 57 in ED/SA- group (SCID 1 used in Sample 1 does not assess ADHD). † Wilcoxon rank sum test, ‡ Fisher’s exact test, § Pearson’s chi squared test