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Table 3 Domains of social cognition in individuals with 22q11DS linked to other variables

From: Social cognition in individuals with 22q11.2 deletion syndrome and its link with psychopathology and social outcomes: a review

Social Cognition

Author

N

Age M (SD), (range)

IQ (SD), (range)

Task

Variable

Association

    

EP

  

Vangkilde et al. (2016) [49]

29

15.7 (2.8), (−)

79.52 (−), (35–113)

ERT

IQ

r = 0.43, p = 0.02

Zaharia et al. (2018) [58]

75

T1 12.81 (3.57),

(−)

71.96 (11.25),

(−)

Face Discrimination Task

IQ

0

Shashi et al. (2012) [53]

66

10.5 (2.6), (−)

(−)

DANVA

IQ

0

Badoud et al. (2017) [55]

29

17.79 (2.89), (11–21)

75.33 (11.66), (−)

Pictures of Facial Affect

IQ

0

Vangkilde et al. (2016) [49]

29

15.7 (2.8), (−)

79.52 (−), (35–113)

ERT

age

F = 10.58, p = 0.002

Campbell et al. (2011) [50]

50

10.99 (2.9), (6–17)

65.8 (9.3), (40–94)

Face Process Skills Battery

  
    

Identity

age

beta = 0.235, p < 0.005

    

Gaze

age

beta = 0.226, p < 0.02

    

Facial speech

age

beta = 0.242, p < 0.03

Zaharia et al. (2018) [58]

75

T1 12.81 (3.57),

(−)

71.96 (11.25),

(−)

Face Discrimination Task

age

d.r.

Badoud et al. (2017) [55]

29

17.79 (2.89), (11–21)

75.33 (11.66),

(−)

Picturres of Facial Affect

age

0

Campbell et al. (2011) [50]

50

10.99 (2.9), (6–17)

65.8 (9.3), (40–94)

Face Process Skills Battery

WM

r = 0.44, p < 0.001

Campbell et al. (2011) [50]

50

10.99 (2.9), (6–17)

65.8 (9.3), (40–94)

Face Process Skills Battery

grammar reception

r = 0.646, p < 0.0005

Shashi et al. (2012) [53]

66

10.5 (2.6), (−)

(−)

DANVA

EF

0

Shashi et al. (2012) [53]

66

10.5 (2.6), (−)

(−)

DANVA

verbal learning and memory

0

Shashi et al. (2012) [53]

66

10.5 (2.6), (−)

(−)

DANVA

sustained attention

0

    

ToM

  

Ho et al. (2012) [52]

34

17.1 (1.9), (14–22)

74.5 (13.2),

(−)

The Animations Task:

  
    

Intentionality (SUNY)

IQ

r = 0.511, p < 0.01

    

Appropriatedness (SUNY)

IQ

r = 0.463, p < 0.01

    

Appropriatedness (random)

IQ

r = 0.453, p < 0.01

Ho et al. (2012) [52]

29

13.7 (5.5), (6–25)

80.5 (13.7),

(−)

The Animations Task:

  
    

Intentionality (UCLA)

IQ

0

    

Appropriatedness (UCLA)

IQ

0

Vangkilde et al. (2016) [49]

29

15.7 (2.8), (−)

79.52 (−), (35–113)

TASIT

IQ

0

Badoud et al. (2017) [55]

29

17.79 (2.89), (11–21)

75.33 (11.66),

(−)

The Director Task

IQ

0

Campbell et al. (2011) [50]

50

10.99 (2.9), (6–17)

65.8 (9.3), (40–94)

False-belief stories

age

r = 0.61, p < 0.0005

Vangkilde et al. (2016) [49]

29

15.7 (2.8), (−)

79.52 (−), (35–113)

TASIT

age

r = 0.35, p = 0.07

Ho et al. (2012) [52]

63

  

The Animations Task:

  

(SUNY)

34

17.1 (1.9), (14–22)

74.5 (13.2),

(−)

Intentionality (SUNY, UCLA)

age

0

(UCLA)

29

13.7 (5.5), (6–25)

80.5 (13.7),

(−)

Appropriatedness (SUNY, UCLA)

age

0

Badoud et al. (2017) [55]

29

17.79 (2.89), (11–21)

75.33 (11.66),

(−)

The Director Task

age

0

Campbell et al. (2015) [54]

24

16.75 (3.14), (12–21)

75.9 (14.9), (56–115)

PST (false-belief stories)

EF

beta = 0.44, p < 0.01

Campbell et al. (2011) [50]

50

10.99 (2.9), (6–17)

65.8 (9.3), (40–94)

False belief-stories

grammar reception

r = 0.347, p < 0.015

  1. DANVA Diagnostic Analysis of Non-Verbal Accuracy, d.r. descriptive report, EAT Emotion Attribution Task, EF executive function, EP emotion processing, ERT Emotion Recognition Task, FERT Facial Emotion Recognition Test, PST Picture Sequencing Task, TASIT The Awareness of Social Inference Test, ToM theory of mind, WM working memory, 0 no significant association (p > 0.05)