|  | Depression | ||
---|---|---|---|---|
 | All | Yes | No | P - value a |
N | 283 | 29 | 254 | Â |
Age (years) | (18–59) | 49 (38, 53) | 42 (31, 50) | 0.036 |
Diabetes duration (years) | (1–55) | 21 (11, 35) | 20 (10, 29) | 0.45 |
Sex | ||||
 Women | 124 (44) | 13 (45) | 111 (44) | > 0.99 b |
 Men | 159 (56) | 16 (55) | 143 (56) | |
Depression | 29 (10) | – | – | – |
sTWEAK (ng/ml) c | (0.5–1618) | 1.5 (1.2, 2.9) | 2.7 (1.3, 13.4) | 0.017 |
Galectin-3 (ng/ml) d | (0.001–100.0) | 1.3 (0.8, 3.0) | 0.9 (0.5, 1.6) | 0.011 |
High galectin-3 (≥2.6 ng/ml) d | 41 (15) | 10 (34) | 31 (13) | 0.005 b |
HbA1c | ||||
 mmol/mol | (25–110) | 68 (55, 73) | 63 (54, 70) | 0.056 |
 % | (4.4–12.2) | 8.4 (7.2, 8.8) | 7.9 (7.1, 8.5) | |
High HbA1c (> 70 mmol/mol (> 8.6%)) | 75 (26) | 13 (45) | 62 (24) | 0.026 b |
Total cholesterol (mmol/l) | (2.1–10.9) | 4.3 (4.0, 4.8) | 4.6 (4.1, 5.2) | 0.044 |
LDL-cholesterol (mmol/l) | (0.6–8.3) | 2.8 (2.2, 3.2) | 2.8 (2.4, 3.3) | 0.37 |
Triglycerides (mmol/l) | (0.06–5.9) | 0.9 (0.7, 1.5) | 0.9 (0.7, 1.2) | 0.35 |
HDL-cholesterol (mmol/l) | (0.3–2.7) | 1.3 (1.2, 1.6) | 1.6 (1.3, 1.8) | 0.015 |
Triglycerides/HDL-cholesterol ratio | (0.04–5.9) | 0.6 (0.5–1.4) | 0.6 (0.4–0.9) | 0.23 |
S-Creatinine (μmol/l) e | (28–182) | 72 (63, 80) | 70 (62, 78) | 0.94 |
Abdominal obesity f | 46 (17) | 6 (21) | 40 (16) | 0.43 b |
BMI (kg/m2) g | (17.8–45.2) | 23.8 (21.8, 27.3) | 24.8 (22.8, 27.5) | 0.21 |
Systolic BP (mm Hg) | (90–160) | 120 (112, 135) | 120 (110, 130) | 0.99 |
Diastolic BP (mm Hg) | (55–100) | 70 (68, 78) | 70 (70, 75) | 0.90 |
Hypoglycemia (severe episodes) | 12 (4) | 2 (7) | 10 (4) | 0.36 b |
Smoking h | 28 (10) | 5 (18) | 23 (10) | 0.19 b |
Physical inactivity i | 29 (11) | 5 (18) | 24 (10) | 0.20 b |
Continuous subcutaneous insulin infusion | 25 (9) | 3 (10) | 22 (9) | 0.73 b |
Antidepressants | 22 (8) | 9 (31) | 13 (5) | < 0.001 b |
Lipid lowering drugs | 130 (46) | 14 (48) | 116 (46) | > 0.84 b |
Antihypertensive drugs | 89 (31) | 10 (34) | 79 (31) | 0.68 b |
Cardiovascular complications | 10 (4) | 4 (14) | 6 (2) | 0.012 b |