|
N
|
283
|
29
|
254
| |
|
Age (years)
|
(18–59)
|
49 (38, 53)
|
42 (31, 50)
|
0.036
|
|
Diabetes duration (years)
|
(1–55)
|
21 (11, 35)
|
20 (10, 29)
|
0.45
|
|
Sex
|
|
Women
|
124 (44)
|
13 (45)
|
111 (44)
|
> 0.99 b
|
|
Men
|
159 (56)
|
16 (55)
|
143 (56)
|
|
Depression
|
29 (10)
|
–
|
–
|
–
|
|
sTWEAK (ng/ml) c
|
(0.5–1618)
|
1.5 (1.2, 2.9)
|
2.7 (1.3, 13.4)
|
0.017
|
|
Galectin-3 (ng/ml) d
|
(0.001–100.0)
|
1.3 (0.8, 3.0)
|
0.9 (0.5, 1.6)
|
0.011
|
|
High galectin-3 (≥2.6 ng/ml) d
|
41 (15)
|
10 (34)
|
31 (13)
|
0.005 b
|
|
HbA1c
|
|
mmol/mol
|
(25–110)
|
68 (55, 73)
|
63 (54, 70)
|
0.056
|
|
%
|
(4.4–12.2)
|
8.4 (7.2, 8.8)
|
7.9 (7.1, 8.5)
|
|
High HbA1c (> 70 mmol/mol (> 8.6%))
|
75 (26)
|
13 (45)
|
62 (24)
|
0.026 b
|
|
Total cholesterol (mmol/l)
|
(2.1–10.9)
|
4.3 (4.0, 4.8)
|
4.6 (4.1, 5.2)
|
0.044
|
|
LDL-cholesterol (mmol/l)
|
(0.6–8.3)
|
2.8 (2.2, 3.2)
|
2.8 (2.4, 3.3)
|
0.37
|
|
Triglycerides (mmol/l)
|
(0.06–5.9)
|
0.9 (0.7, 1.5)
|
0.9 (0.7, 1.2)
|
0.35
|
|
HDL-cholesterol (mmol/l)
|
(0.3–2.7)
|
1.3 (1.2, 1.6)
|
1.6 (1.3, 1.8)
|
0.015
|
|
Triglycerides/HDL-cholesterol ratio
|
(0.04–5.9)
|
0.6 (0.5–1.4)
|
0.6 (0.4–0.9)
|
0.23
|
|
S-Creatinine (μmol/l) e
|
(28–182)
|
72 (63, 80)
|
70 (62, 78)
|
0.94
|
|
Abdominal obesity f
|
46 (17)
|
6 (21)
|
40 (16)
|
0.43 b
|
|
BMI (kg/m2) g
|
(17.8–45.2)
|
23.8 (21.8, 27.3)
|
24.8 (22.8, 27.5)
|
0.21
|
|
Systolic BP (mm Hg)
|
(90–160)
|
120 (112, 135)
|
120 (110, 130)
|
0.99
|
|
Diastolic BP (mm Hg)
|
(55–100)
|
70 (68, 78)
|
70 (70, 75)
|
0.90
|
|
Hypoglycemia (severe episodes)
|
12 (4)
|
2 (7)
|
10 (4)
|
0.36 b
|
|
Smoking h
|
28 (10)
|
5 (18)
|
23 (10)
|
0.19 b
|
|
Physical inactivity i
|
29 (11)
|
5 (18)
|
24 (10)
|
0.20 b
|
|
Continuous subcutaneous insulin infusion
|
25 (9)
|
3 (10)
|
22 (9)
|
0.73 b
|
|
Antidepressants
|
22 (8)
|
9 (31)
|
13 (5)
|
< 0.001 b
|
|
Lipid lowering drugs
|
130 (46)
|
14 (48)
|
116 (46)
|
> 0.84 b
|
|
Antihypertensive drugs
|
89 (31)
|
10 (34)
|
79 (31)
|
0.68 b
|
|
Cardiovascular complications
|
10 (4)
|
4 (14)
|
6 (2)
|
0.012 b
|
