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Table 2 Elimination analyses between log transformed sTWEAK, 4 levels of dichotomized sTWEAK and depression

From: Low levels of soluble TWEAK, indicating on-going inflammation, were associated with depression in type 1 diabetes: a cross-sectional study

  Depression
  N (%) Yes
(Median (q1, q3) or N (%))
No
(Median (q1, q3) or N (%))
P - value a COR (95% CI) P - value b AOR (95% CI) P - value c
sTWEAK (Lg10) 0.2 (0.1–0.5) 0.4 (0.1–1.1) 0.017 d 0.4 (0.2–0.9) 0.027 1.7 (0.4–7.6) 0.48
sTWEAK < 3.9 (ng/ml) 167 (60) 24 (83) 143 (57) 0.009 3.6 (1.3–9.6) 0.012 1.4 (0.4–5.0) 0.61
sTWEAK < 6.1 (ng/ml) 181 (65) 25 (86) 156 (63) 0.013 3.7 (1.3–11.0) 0.018 0.5 (0.04–6.2 0.58
sTWEAK < 7.2 (ng/ml) 195 (70) 27 (93) 168 (68) 0.003 6.5 (1.5–28.0) 0.012 6.5 (1.5–28.0) 0.012
sTWEAK < 11.9 (ng/ml) 209 (75) 27 (93) 182 (73) 0.021 5.0 (1.2–21.5) 0.032 0.0 (0.0-) > 0.99
  1. N = 278. a Fisher’s Exact Test unless indicated. b Logistic regression analysis (simple)
  2. c Multiple logistic regression analysis (Backward: Wald). d Mann-Whitney U test