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Table 2 Elimination analyses between log transformed sTWEAK, 4 levels of dichotomized sTWEAK and depression

From: Low levels of soluble TWEAK, indicating on-going inflammation, were associated with depression in type 1 diabetes: a cross-sectional study

 

Depression

 

N (%)

Yes

(Median (q1, q3) or N (%))

No

(Median (q1, q3) or N (%))

P - value a

COR (95% CI)

P - value b

AOR (95% CI)

P - value c

sTWEAK (Lg10)

–

0.2 (0.1–0.5)

0.4 (0.1–1.1)

0.017 d

0.4 (0.2–0.9)

0.027

1.7 (0.4–7.6)

0.48

sTWEAK < 3.9 (ng/ml)

167 (60)

24 (83)

143 (57)

0.009

3.6 (1.3–9.6)

0.012

1.4 (0.4–5.0)

0.61

sTWEAK < 6.1 (ng/ml)

181 (65)

25 (86)

156 (63)

0.013

3.7 (1.3–11.0)

0.018

0.5 (0.04–6.2

0.58

sTWEAK < 7.2 (ng/ml)

195 (70)

27 (93)

168 (68)

0.003

6.5 (1.5–28.0)

0.012

6.5 (1.5–28.0)

0.012

sTWEAK < 11.9 (ng/ml)

209 (75)

27 (93)

182 (73)

0.021

5.0 (1.2–21.5)

0.032

0.0 (0.0-)

> 0.99

  1. N = 278. a Fisher’s Exact Test unless indicated. b Logistic regression analysis (simple)
  2. c Multiple logistic regression analysis (Backward: Wald). d Mann-Whitney U test