Table 1 Patient characteristics
Eligible patients | Medical examination follow-up patients (PS matched) | Long-term follow-up patients (PS matched) | ||||
|---|---|---|---|---|---|---|
With atypical antipsychotic (N = 2444) | Without atypical antipsychotic (N = 1020) | With atypical antipsychotic (N = 185) | Without atypical antipsychotic (N = 185) | With atypical antipsychotic (N = 889) | Without atypical antipsychotic (N = 889) | |
Age | ||||||
< 25 years | 131 (5.4%) | 51 (5.0%) | 0 | 0 | 14 (1.6%) | 26 (2.9%) |
25–29 years | 244 (10.0%) | 67 (6.6%) | 0 | 0 | 47 (5.3%) | 54 (6.1%) |
30–34 years | 280 (11.5%) | 88 (8.6%) | 0 | 0 | 67 (7.5%) | 76 (8.6%) |
35–39 years | 353 (14.4%) | 108 (10.6%) | 38 (20.5%) | 28 (15.1%) | 112 (12.6%) | 99 (11.1%) |
40–49 years | 947 (38.8%) | 369 (36.2%) | 85 (46%) | 91 (49.2%) | 381 (42.9%) | 345 (38.8%) |
50–59 years | 443 (18.1%) | 279 (27.4%) | 55 (29.7%) | 59 (31.9%) | 235 (26.4%) | 245 (27.6%) |
> =60 years | 46 (1.9%) | 58 (5.7%) | 7 (3.8%) | 7 (3.8%) | 33 (3.7%) | 44 (5%) |
Mean (years) | 40.9 ± 9.8 | 43.9 ± 10.5 | 46.3 ± 7 | 47.0 ± 6.8 | 44.4 ± 9.1 | 44.3 ± 9.8 |
Sex (male %) | 1608 (65.8%) | 676 (66.3%) | 127 (68.6%) | 133 (71.9%) | 594 (66.8%) | 570 (64.1%) |
Year of diagnosis | ||||||
-2007 | 25 (1.0%) | 15 (1.5%) | 0 | 0 | 6 (0.7%) | 6 (0.7%) |
2008–2010 | 327 (13.4%) | 83 (8.1%) | 16 (8.7%) | 21 (11.4%) | 69 (7.8%) | 70 (7.9%) |
2011–2013 | 693 (28.4%) | 249 (24.4%) | 62 (33.5%) | 47 (25.4%) | 229 (25.8%) | 226 (25.4%) |
2014- | 1399 (57.2%) | 673 (66%) | 107 (57.8%) | 117 (63.2%) | 585 (65.8%) | 587 (66%) |
SBP (mmHg) | 118.2 ± 15.4 | 119.6 ± 16.3 | 120.5 ± 14.9 | 121.1 ± 16.4 | 119.5 ± 16.3 | 119.1 ± 16 |
DBP (mmHg) | 72.9 ± 11.4 | 73.9 ± 11.5 | 75.1 ± 10.9 | 75.8 ± 12.2 | 74.3 ± 11.7 | 73.9 ± 11.4 |
LDL-C (mg/dL) | 119.6 ± 32.5 | 118.4 ± 32.5 | 118.6 ± 29.4 | 123 ± 32.1 | 118.4 ± 31.6 | 118.7 ± 32.1 |
HDL-C (mg/dL) | 62.8 ± 17.5 | 62.3 ± 17.0 | 63.3 ± 16.4 | 62.2 ± 15.8 | 62.6 ± 18 | 62.7 ± 16.8 |
eGFR (mL/min/1.73 m2) | 98.3 ± 18.1 | 96.7 ± 19.5 | 92.7 ± 16.4 | 94.7 ± 18.3 | 96.7 ± 17.7 | 97.5 ± 19 |
HbA1c (%) | 5.5 ± 0.6 | 5.5 ± 0.8 | 5.6 ± 0.7 | 5.5 ± 0.6 | 5.5 ± 0.7 | 5.5 ± 0.7 |
TC (mg/dL) | 205.5 ± 39.0 | 203.1 ± 38.4 | 205.2 ± 33.9 | 207.6 ± 35.9 | 204 ± 38.5 | 203.4 ± 37.3 |
TG (mg/dL) | 120.5 ± 106.9 | 118 ± 100.3 | 126.8 ± 131 | 123.8 ± 85.9 | 119.8 ± 105.5 | 115.4 ± 86.9 |
BMI (kg/m2) | 22.8 ± 3.9 | 22.9 ± 4.0 | 23.4 ± 3.9 | 23.4 ± 4.3 | 23 ± 4.1 | 22.9 ± 4 |
Suita score (LDL) | 30.5 ± 10.4 | 32.8 ± 11.0 | 31.4 ± 10.4 | 32.7 ± 10.3 | 31.8 ± 10.4 | 32.2 ± 10.9 |
Framingham score (LDL) | 0.2 ± 5.0 | 1.2 ± 5.0 | 1.1 ± 4.3 | 1.7 ± 4.1 | 1.0 ± 4.8 | 1.0 ± 5.1 |
JALS score | 20.3 ± 15.3 | 22.6 ± 16.1 | 21.1 ± 14.7 | 22.1 ± 14.9 | 21.2 ± 14.9 | 21.8 ± 15.9 |
Smoking habits | 646 (26.4%) | 274 (26.9%) | 51 (27.6%) | 52 (28.1%) | 245 (27.6%) | 246 (27.7%) |
Diabetes | 88 (3.6%) | 60 (5.9%) | 13 (7%) | 5 (2.7%) | 46 (5.2%) | 44 (4.9%) |