Variables | All patients | SUA tertiles | P | Tertile 1 vs Tertile 2 | Tertile 1 vs Tertile 3 | Tertile 2 vs Tertile 3 | ||
---|---|---|---|---|---|---|---|---|
Tertile 1, n=107 (≤ 293) | Tertile 2, n=107 (294–374) | Tertile 3, n=106 (≥ 375) | ||||||
SUA (umol/L), mean±SD | 340.08 ± 93.05 | 246.16 ± 34.50 | 330.18 ± 22.96 | 444.87 ± 66.30 | <0.001d | p<0.001e | <0.001e | <0.001e |
C-NDDI-E score, median (IQR) | 7 (6, 10) | 8, (6, 13) | 7 (6, 10) | 7 (6, 9) | <0.001c | 0.016b | <0.001b | 0.236b |
GAD-7 score, median (IQR) | 3 (1, 7) | 5 (1, 9) | 3 (0, 6) | 2 (0, 4) | 0.002c | 0.020b | <0.001b | 0.302b |
Age (Years), mean±SD | 37.88 ± 15.94 | 40.26 ± 16.35 | 40.63 ± 16.65 | 32.71 ± 13.48 | <0.001d | 0.864e | <0.001e | <0.001e |
Gender-female, n(%) | 134 (41.9) | 77 (72.0) | 40 (37.4) | 17 (16.0) | <0.001a | <0.001a | <0.001a | <0.001a |
BMI (Kg/M2), mean±SD | 23.48 ± 3.82 | 22.43 ± 3.57 | 23.74 ± 3.53 | 24.28 ± 4.13 | 0.001d | 0.011e | <0.001e | 0.293e |
Marital status-married, n(%) | 205 (64.1) | 78 (72.9) | 69 (64.5) | 58 (54.7) | 0.022a | 0.185a | 0.006a | 0.146a |
Educational level, n(%) | Â | Â | Â | Â | <0.001a | 0.088a | <0.001a | 0.023a |
 University and above | 95 (29.7) | 25 (23.4) | 27 (25.2) | 43 (40.6) |  |  |  |  |
 Middle school | 193 (60.3) | 62 (57.9) | 71 (66.4) | 60 (56.6) |  |  |  |  |
 Primary school and below | 32 (10) | 20 (18.7) | 9 (8.4) | 3 (2.8) |  |  |  |  |
Residence-rural area, n(%) | 115 (35.9) | 45 (42.1) | 31 (29.0) | 39 (36.8) | 0.133a | 0.046a | 0.432a | 0.224a |
Per capita monthly family income (Yuan), n(%) | Â | Â | Â | Â | 0.098a | 0.745a | 0.057a | 0.050a |
 <1000 | 31 (9.7) | 14 (13.1) | 12 (11.2) | 5 (4.7) |  |  |  |  |
 1000–5000 | 230 (71.9) | 75 (70.1) | 80 (74.8) | 75 (70.8) |  |  |  |  |
 >5000 | 59 (18.4) | 18 (16.8) | 15 (14.0) | 26 (24.5) |  |  |  |  |
Age at onset (Years),median (IQR) | 30 (18, 46) | 30 (18, 47) | 36 (19, 50) | 24 (17, 39) | 0.005c | 0.406b | 0.019b | 0.002b |
Disease duration (Years),median (IQR) | 2 (1, 6) | 2 (1, 7) | 2 (1, 5) | 2 (1, 5) | 0.55c | 0.409b | 0.301b | 0.841b |
Seizure type-focal onset, n(%) | 266 (83.1) | 93 (86.9) | 86 (80.4) | 87 (82.1) | 0.415a | 0.196a | 0.369a | 0.751a |
Seizure frequency over the last year, n(%) | Â | Â | Â | Â | 0.015a | 0.151a | 0.002a | 0.279a |
 Seizure-feee | 63 (19.7) | 20 (18.7) | 21 (19.6) | 22 (20.8) |  |  |  |  |
 1–11 | 164 (51.2) | 44 (41.4) | 56 (52.3) | 64 (60.4) |  |  |  |  |
 >12 | 93 (29.1) | 43 (40.2) | 30 (28.0) | 20 (18.9) |  |  |  |  |
Treatment-monotherapy, n(%) | 286 (89.4) | 93 (86.9) | 96 (89.7) | 97 (91.5) | 0.548a | 0.523a | 0.280a | 0.654a |
>50% nocturnal seizures, n(%) | 120 (37.5) | 38 (35.5) | 38 (35.5) | 44 (41.5) | 0.581a | 1a | 0.369a | 0.369a |