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Table 4 MRI Parameters

From: Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative

MRI Scanner

 Brazil

Philips Achieva 3.0 T

 India

Philips Ingenia 3.0 T CX

 Netherlands

GE 3.0 T Discovery MR750

 South Africa

Siemens MAGNETOM Skyra 3.0 T

 U.S.

GE 3.0 T SIGNA Premier

Head coil

32-channel or 48-channel#

MRI Sequences

 Structural T1

3D sagittal T1-weighted MP-RAGE according to ADNI-3 protocol (1 × 1 × 1 mm resolution)

 rs-fMRI

T2*-weighted echo-planar images while subjects are awake and keep their eyes closed (10 min, TR = 2200 ms, TE = 28 ms, 3.3 × 3.3 mm in-plane resolution, 3 mm slices with 0.3 mm gap)

 DWI

multi-shell single spin echo DWI (80 interleaved volumes: 7 b0, 25 b1000, 24 b2000, 24 b3000, 2.5 × 2.5 × 2.5 mm)

 PSIR

T1-weighted image with improved SNR and gray-white matter contrast (1 × 1 × 1 mm resolution)

  1. All sites use a 32-channel head coil, except NYC which uses a 48-channel head coil. Abbreviations: rs-fMRI Resting-state functional Magnetic Resonance Imaging, DWI Diffusion weighted Imaging, PSIR Phase sensitive inversion recovery