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Table 2 Patients with Bipolar Disorder compared to Matched Controls

From: Chronic pain diagnoses and opioid dispensings among insured individuals with serious mental illness

Characteristic

Patients with Bipolar Disorder

(N = 38,117)

n(%)/Mean ± SD

Matched Controls

(N = 38,115)

n(%)/Mean ± SD

Test Statistic

p-value

Age

42.7+  13.2

42.7+  13.3

t = −0.20

0.84

Sex

 Male

12,530(32.9%)

12,530(32.9%)

χ2 = 0

0.99

 Female

25,585 (67.1%)

25,583 (67.1%)

Medicare

6386 (16.8%)

6383 (16.8%)

χ2 = 0

0.98

Race

 White/Caucasian

27,348(71.8%)

18,408 (48.3%)

χ2 = 5450.33

< 0.0001

 Black/African-American

3410 (9.0%)

3594 (9.4%)

 Asian

1782 (4.7%)

4993 (13.1%)

 Pacific Islander

281 (0.7%)

453 (1.2%)

 Native American

499 (1.3%)

281 (0.7%)

 Other

94 (0.3%)

117 (0.3%)

 Unknown

4694 (12.3%)

10,262 (27.0%)

Ethnicity (Hispanic)

5473 (14.4%)

8307 (21.8%)

χ2 = 711.63

< 0.0001

Neighborhood Income

  < $40,000 per year

4985 (13.1%)

4835(12.7%)

χ2 = 0.41

0.52

  > $40,000 per year

32,544 (85.4%)

32,006 (84.0%)

Charlson Comorbidity Index

0.55+  1.10

0.28+  0.81

t = 39.21

< 0.0001

Total healthcare utilization in last 6 mo

8.6+  11.3

2.4+  4.8

t = 99.04

< 0.0001

Pain conditions

 Any Pain

23,423(61.5%)

15,342 (40.3%)

χ2 = 3426.65

< 0.0001

 Back pain

7756 (20.4%)

3650 (9.6%)

χ2 = 1737.92

< 0.0001

 Neck pain

3713 (9.7%)

1805 (4.7%)

χ2 = 711.12

< 0.0001

 Limb/extremity pain, arthritis

12,052(31.6%)

7401 (19.4%)

χ2 = 1492.66

< 0.0001

 Fibromyalgia/widespread muscle

2384 (6.3%)

663 (1.7%)

χ2 = 1012.43

< 0.0001

 Headache

5000 (13.1%)

1845 (4.8%)

χ2 = 1597.48

< 0.0001

 Orofacial/ear/temporomandibular

477 (1.3%)

237 (0.6%)

χ2 = 81.42

< 0.0001

 Abdominal/bowel pain

5777 (15.2%)

2821 (7.4%)

χ2 = 1145.30

< 0.0001

 Chest pain

3009 (7.9%)

1348 (3.5%)

χ2 = 671.51

< 0.0001

 Urogenital/pelvic/menstrual pain

1925 (5.1%)

959 (2.5%)

χ2 = 336.23

< 0.0001

 Fractures/contusions/sprains/strains

5567 (14.6%)

2743(7.2%)

χ2 = 1076.93

< 0.0001

 Other painful conditionsa

4137 (10.9%)

2034 (5.3%)

χ2 = 779.68

< 0.0001

Chronic opioid useb

3961 (10.4%)

1156 (3.0%)

χ2 = 1648.10

< 0.0001

  1. aIncludes sickle cell disease, complex regional pain syndrome, systemic lupus erythematosus, acquired deformities (excluding spinal disorders), spinal cord injury, lyme disease, neuropathic pain
  2. bChronic use defined by 70+ days supply in a 90-day period, receiving 6+ dispenses in a year