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Table 3 Patients with Schizophrenia compared to Matched Controls

From: Chronic pain diagnoses and opioid dispensings among insured individuals with serious mental illness

Characteristic

Patients with Schizophrenia

(N = 12,916)

n(%)/Mean ± SD

Matched Controls

(N = 25,791)

n(%)/Mean ± SD

Test Statistic

p-value

Age

42.3+  13.8

42.3+  13.9

t = 0.34

0.73

Sex

 Male

7250 (56.1%)

14,459 (56.1%)

χ2 = 0.02

0.90

 Female

5666 (43.9%)

11,332 (43.9%)

Medicare

5144 (39.8%)

10,247 (39.7%)

χ2 = 0.03

0.86

Race

 White/Caucasian

6889 (53.3%)

12,770 (49.5%)

χ2 = 1021.25

< 0.0001

 Black/African-American

2476 (19.2%)

2724 (10.6%)

 Asian

1317 (10.2%)

3008 (11.7%)

 Pacific Islander

153 (1.2%)

343 (1.3%)

 Native American

138 (1.1%)

204 (0.8%)

 Other

28 (0.2%)

44 (0.2%)

 Unknown

1907 (14.8%)

6696 (26.0%)

Ethnicity (Hispanic)

2511 (19.4%)

6045 (23.4%)

χ2 = 79.87

< 0.0001

Neighborhood Income

  < $40,000 per year

2404 (18.6%)

3444 (13.4%)

χ2 = 170.42

< 0.0001

  > $40,000 per year

10,345(80.1%)

21,650 (83.9%)

Charlson Comorbidity Index

0.63+  1.18

0.43+  1.07

t = −16.58

< 0.0001

Total healthcare utilization in last 6 mo

7.9+  10.9

2.6+  5.6

t = −63.60

< 0.0001

Pain conditions

 Any Pain

6092 (47.2%)

10,835(42.0%)

χ2 = 92.96

< 0.0001

 Back pain

1855 (14.4%)

2687 (10.4%)

χ2 = 129.23

< 0.0001

 Neck pain

754 (5.8%)

1228 (4.8%)

χ2 = 20.52

< 0.0001

 Limb/extremity pain, arthritis

2942 (22.8%)

5312 (20.6%)

χ2 = 24.41

< 0.0001

 Fibromyalgia/widespread muscle

386 (3.0%)

463 (1.8%)

χ2 = 57.13

< 0.0001

 Headache

973 (7.5%)

1264 (4.9%)

χ2 = 109.52

< 0.0001

 Orofacial/ear/temporomandibular

112 (0.9%)

150 (0.6%)

χ2 = 10.44

0.0012

 Abdominal/bowel pain

1497 (11.6%)

1907 (7.4%)

χ2 = 188.93

< 0.0001

 Chest pain

975 (7.6%)

1137 (4.4%)

χ2 = 164.51

< 0.0001

 Urogenital/pelvic/menstrual pain

280 (2.2%)

442 (1.7%)

χ2 = 9.69

0.0018

 Fractures/contusions/sprains/strains

1392 (10.8%)

1968 (7.6%)

χ2 = 107.50

< 0.0001

 Other painful conditionsa

1117 (8.7%)

1884 (7.3%)

χ2 = 21.71

< 0.0001

Chronic opioid useb

845 (6.5%)

1299 (5.0%)

χ2 = 37.29

< 0.0001

  1. aIncludes sickle cell disease, Complex Regional Pain Syndrome, systemic lupus erythematosus, acquired deformities (excluding spinal disorders), spinal cord injury, Lyme disease, Neuropathic pain
  2. bChronic use defined by 70+ days supply in a 90 day period, receiving 6+ dispenses in a year