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Table 1 Demographic and clinical characteristics of the patient sample, and comparisons between non-clozapine and clozapine groups

From: Daily functioning and symptom factors contributing to attitudes toward antipsychotic treatment and treatment adherence in outpatients with schizophrenia spectrum disorders

 

Total (n = 276)

Non-clozapine group (n = 161)

Clozapine group (n = 115)

 

p

Mean or n (%)

S.D.

Mean or n (%)

S.D.

Mean or n (%)

S.D.

 

Male sex n (%)

152 (55.1%)

 

85 (52.8%)

 

67 (58.3%)

 

0.368

Schizophrenia

190 (68.8%)

 

89 (55.3%)

 

101 (87.8%)

 

< 0.001

Schizoaffective disorder

49 (17.8%)

 

36 (22.4%)

 

13 (11.3%)

 

0.018

Other schizophrenia spectrum disorder

37 (13.4%)

 

36 (22.4%)

 

1 (0.9%)

 

< 0.001

Age

44.9

12.6

47.2

12.5

41.8

12.1

0.001

Chlorpromazine equivalents, mg

582.5

423.2

415.3

344.1

816.7

413.6

< 0.001

ANT-attitude (0–100)

72.0

16.5

71.1

17.0

73.3

15.8

0.334

ANT-adherence (over 75%)

228 (82.6%)

 

124 (77.0%)

 

104 (90.4%)

 

0.004

ANT-insight (0–100)

49.5

24.9

46.5

24.7

53.7

24.7

0.024

ANT-side effects (0–100)

62.4

24.0

64.0

25.5

60.2

21.6

0.175

BPRS (24–168)

34.6

7.8

34.4

8.1

34.9

7.4

0.363

BPRS positive symptoms (7–49)

10.2

4.3

10.1

4.4

10.3

4.1

0.58

HoNOS total (0–48)

7.2

4.5

7.1

4.5

7.3

4.4

0.712

HoNOS behaviour (0–12)

0.3

0.7

0.4

0.8

0.2

0.6

0.02

HoNOS impairment (0–8)

1.8

1.6

1.8

1.7

1.7

1.5

0.853

HoNOS symptoms (0–12)

3.0

2.2

2.9

2.2

3.3

2.2

0.139

HoNOS social (0–16)

1.2

1.3

1.2

1.4

1.2

1.3

0.591

SANS (0–15)

1.1

1.0

1.1

1.0

1.1

1.0

0.712

GAF (0–100)

56.1

12.6

57.6

12.5

54.0

12.5

0.022

ADL (5–20)

5.7

1.3

5.8

1.5

5.4

0.9

0.061

IADL (5–20)

7.6

2.8

7.8

3.1

7.3

2.3

0.422

Social functioning (4–16)

5.5

1.9

5.6

1.9

5.5

1.8

0.897

  1. High score in ANT -attitude, −insight and -side effect indicates positive attitudes toward medication, better sickness awareness and less experienced side effects. High score in BPRS, BPRS positive symptoms, HoNOS total, HoNOS behaviour/impairment/symptoms/social and SANS indicates more severe symptom. High score in GAF indicates better functioning. High score in ADL, IADL and social functioning indicates more problems with activities of daily living