Skip to main content

Table 4 Tests of Model Effects between groups and ECT treatment times using generalized estimating equations (GEEs)

From: Comparison of the target-controlled infusion and the manual infusion of propofol anesthesia during electroconvulsive therapy: an open-label randomized controlled trial

 

TCI versus MI

ECT treatment number

TCI × ECT treatment number versus MI × ECT treatment number

Age

Male versus Female

β (SE)

β (SE)

β (SE)

β (SE)

β (SE)

Total dose of propofol (mg/kg)a

1.82 (0.22)***

0.02 (0.02)

0.02 (0.03)

−0.00 (0.01)

0.29 (0.16)

Stimulus dose (mC)

−2.94 (33.6)

22.53 (2.54)***

10.82 (3.64)**

0.68 (1.13)

9.82 (29.6)

Recovery time (min)

5.09 (2.17)*

−0.10 (0.26)

−0.44 (0.38)

0.06 (0.05)

2.40 (1.26)

ASTI (min)

0.74 (0.32)*

−0.01 (0.04)

0.03 (0.06)

0.00 (0.01)

0.42 (0.17)*

Seizure adequacy (%)

21.82 (7.35)**

−2.42 (0.92)*

−3.78 (1.28)**

0.01 (0.16)

6.23 (3.95)

EEG seizure duration (sec)

9.91 (5.96)*

−0.00 (0.73)

−2.03 (1.04)

−0.27 (0.13)*

− 0.62 (3.31)

Motor seizure duration (sec)

0.45 (4.75)

−0.84 (0.57)

0.23 (0.81)

−0.15 (0.11)

0.35 (2.85)

Ictal HR – baseline HR (beats/min)

−4.53 (8.42)

0.21 (0.96)

−0.26 (1.37)

−0.50 (0.22)*

−3.89 (5.60)

Discharge HR - baseline HR (beats/min)

−7.59 (5.68)

−2.06 (0.69)**

0.02 (0.98)

−0.14 (0.13)

1.39 (3.25)

Ictal SBP– baseline SBP (mmHg)

−11.28 (6.88)

1.01 (0.84)

2.01 (1.19)

−0.23 (0.15)

−17.86 (3.92)***

Discharge SBP– baseline SBP (mmHg)

−6.64 (6.87)

0.77 (0.83)

0.95 (1.18)

0.00 (0.16)

−9.40 (4.04)*

Ictal DBP– baseline DBP (mmHg)

−8.92 (5.07)

−1.00 (0.62)

2.18 (0.88)*

−0.19 (0.11)

−7.10 (2.88)*

Discharge DBP– baseline DBP (mmHg)

−2.97 (4.15)

−0.17 (0.51)

0.07 (0.73)

−0.12 (0.09)

−2.81 (2.24)

  1. *: p < 0.05; **: p < 0.01; ***: p < 0.001
  2. a: Total dose of propofol was total amount of propofol divided by ideal body weight
  3. ASTI anesthetic-stimulation time interval, EEG electroencephalogram, HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure