From: Conditional power of antidepressant network meta-analysis
N_{CP=20%} | N_{CP=80%} | ||||
---|---|---|---|---|---|
Sample size | Sample size | ||||
Trial design | Effect size | Event probability | median [range] | median [range] | |
Efficacy | |||||
Main analysis | r = 1/0 | f_{xyN} | pc_{N} = 0.17 | 250 [49 - 485] | 1586 [894 - 4190] |
Sensitivity analysis | r = 1/1 | f_{xyN} | pc_{N} = 0.17 | 126 [10 - 384] | 1198 [720 - 3464] |
r = 1/2 | f_{xyN} | pc_{N} = 0.17 | 117 [10 - 222] | 994 [624 - 2586] | |
r = 1/0 | f_{xy} d = 0.01 | pc_{N} = 0.17 | 250 [49 - 483] | 1576 [916 - 4176] | |
r = 1/0 | f_{xy} d = 0.1 | pc_{N} = 0.17 | 245 [49 - 509] | 1612 [866 - 4371] | |
r = 1/0 | f_{xy} d = 0.2 | pc_{N} = 0.17 | 242 [49 - 538] | 1644 [817 - 4682] | |
r = 1/0 | f_{xy} d = 0.3 | pc_{N} = 0.17 | 238 [49 - 566] | 1628 [773 - 9660] | |
r = 1/0 | f_{xy} d = 0.5 | pc_{N} = 0.17 | 236 [47 - 622] | 1668 [695 - 9772] | |
r = 1/0 | f_{xy} d = 0.8 | pc_{N} = 0.17 | 228 [44 - 699] | 1754 [595 - 9880] | |
r = 1/0 | f_{xyN} | pc = 0.01 | 706 [51 - 1407] | 3678 [2471 - 10000] | |
r = 1/0 | f_{xyN} | pc = 0.1 | 373 [50 - 741] | 2384 [1370 - 9927] | |
r = 1/0 | f_{xyN} | pc = 0.2 | 212 [48 - 416] | 1367 [781 - 3793] | |
r = 1/0 | f_{xyN} | pc = 0.3 | 136 [43 - 318] | 1044 [599 - 3217] | |
r = 1/0 | f_{xyN} | pc = 0.5 | 96 [36 - 271] | 874 [503 - 2877] | |
Tolerability | |||||
Main analysis | r = 1/0 | f_{xyN} | pc_{N} = 0.57 | 198 [40 - 320] | 791 [521 - 1246] |
Sensitivity analysis | r = 1/1 | f_{xyN} | pc_{N} = 0.57 | 104 [64 - 278] | 738 [414 - 1258] |
r = 1/2 | f_{xyN} | pc_{N} = 0.57 | 102 [81 - 168] | 675 [480 - 1161] | |
r = 1/0 | f_{xy} d = 0.01 | pc_{N} = 0.57 | 207 [41 - 318] | 766 [619 - 1202] | |
r = 1/0 | f_{xy} d = 0.1 | pc_{N} = 0.57 | 192 [40 - 321] | 782 [569 - 1283] | |
r = 1/0 | f_{xy} d = 0.2 | pc_{N} = 0.57 | 181 [40 - 343] | 791 [513 - 1373] | |
r = 1/0 | f_{xy} d = 0.3 | pc_{N} = 0.57 | 170 [39 - 366] | 817 [471 - 1462] | |
r = 1/0 | f_{xy} d = 0.5 | pc_{N} = 0.57 | 146 [39 - 420] | 908 [409 - 1782] | |
r = 1/0 | f_{xy} d = 0.8 | pc_{N} = 0.57 | 121 [40 - 615] | 1027 [320 - 2497] | |
r = 1/0 | f_{xyN} | pc = 0.01 | 319 [41 - 523] | 1258 [824 - 1991] | |
r = 1/0 | f_{xyN} | pc = 0.1 | 153 [41 - 277] | 662 [442 - 1046] | |
r = 1/0 | f_{xyN} | pc = 0.2 | 55 [37 - 117] | 371 [257 - 582] | |
r = 1/0 | f_{xyN} | pc = 0.3 | 40 [32 - 72] | 277 [207 - 435] | |
r = 1/0 | f_{xyN} | pc = 0.5 | 34 [31 - 55] | 227 [192 - 365] |