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Table 2 Comparative profile of male patients with MDD and control participants

From: Role of insulin-like growth factor 1, sex and corticosteroid hormones in male major depressive disorder

Variables

MDD1

Control

P value

Number

54

37

–

Age (year)a

42.4 ± 14.7

39.4 ± 7.0

P = 0.187†

Body mass index (kg/m2)a

24.2 ± 3.1

24.0 ± 3.5

P = 0.661†

Smoker/non smoker

13 / 41

5 / 32

P = 0.214‡

HbA1c (%)a4

5.4 ± 0.5

5.4 ± 0.8

P = 0.970†

Cortisol (μg/dl)a

12.1 ± 4.8

11.1 ± 3.0

P = 0.191†

DHEAS (μg/dl)a2

227.9 ± 108.4

307.4 ± 131.2

P = 0.002†

Cortisol / DHEAS ratioa

0.07 ± 0.05

0.04 ± 0.02

P = 0.001†

IGF1 (ng/ml)a3

171.5 ± 61.8

144.1 ± 39.2

P = 0.011†

Testosterone (ng/ml)a

5.0 ± 1.6

4.9 ± 1.6

P = 0.709†

Estradiol (pg/ml)a

22.4 ± 8.4

26.1 ± 8.5

P = 0.040†

  1. aData are expressed as the mean ± standard deviation. †Unpaired t-test. ‡Chi-squared tests. Abbreviations: 1MDD Major depressive disorder, 2DHEAS Dehydroepiandrosterone and its sulfate, 3IGF1 Insulin-like growth factor 1, 4HbA1c Glycated hemoglobin