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Table 2 Results of ALE analyses on grey matter abnormalities in TS patients

From: Grey matter abnormalities in Tourette syndrome: an activation likelihood estimation meta-analysis

Cluster# Volume (mm3) Peak ALE value Z values Talairach coordinates(x, y, z) Brain regions
Groups with increased grey matter volumes
 1 952 0.019318
0.016552817
5.344082 −12, −30, 10
−14, −28, − 2
(L) Thalamus (61.3% Pulvinar, 2.5% Medial Geniculate Body)
4.7613444
 2 784 0.01593744
0.015419524
4.662963 −2, −6, −6
0, −16, −8
(L) Thalamus (Red Nucleus)
4.5910673
 3 480 0.019446805 5.3822155 12, −30,13 (R) Thalamus (100% Pulvinar)
 4 424 0.016458694 4.751242 16, −28, −2 (R) Thalamus (16.7% Pulvinar)
 5 384 0.015193136 4.555133 20, −22, 68 (R) Precentral Gyrus (BA 4)
 6 336 0.014851548 4.504367 8, −4, −14 (R) Hypothalamus
 7 80 0.010117263 3.6241639 −56, −18, 33 (L) Postcentral Gyrus (BA 2)
 8 80 0.010117263 3.6241639 −36, −34, 45 (L) Inferior Parietal Lobule (BA 40)
 9 64 0.008642835 3.1104991 27, −3, 9 (R) Lentiform Nucleus (Putamen)
 10 64 0.00938297 3.3538606 −38, 4, 12 (L) Insula (BA 13)
Groups with decreased grey matter volumes
 1 208 0.00997 3.9280179 −56, −18, 34 (L) Postcentral Gyrus (BA 2)
 2 96 0.008955 3.6178029 6, 44, 0 (R) Anterior Cingulate (BA 32&24)
 3 96 0.009334 3.8218374 −40, −2, 8 (L) Sub-lobar (Insula)
 4 80 0.009279 3.7407575 0, 33, −26 (L) Medial Frontal Gyrus (BA 11)
 5 80 0.008896 3.611275 −40, 4, 12 (L) Sub-lobar (Insula)
 6 80 0.009279 3.7407575 58, −13, 16 (R) Postcentral Gyrus (BA 43)
 7 56 0.009123 3.6994894 −14, 40, 10 (L) Anterior Cingulate (BA 32)
 8 56 0.009123 3.6994894 −8, −52, 26 (L) Posterior Cingulate (BA 31)
  1. Abbreviations: ALE, activation likelihood estimation; BA, Brodmann area; L, left; R, right