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Table 2 Results of ALE analyses on grey matter abnormalities in TS patients

From: Grey matter abnormalities in Tourette syndrome: an activation likelihood estimation meta-analysis

Cluster#

Volume (mm3)

Peak ALE value

Z values

Talairach coordinates(x, y, z)

Brain regions

Groups with increased grey matter volumes

 1

952

0.019318

0.016552817

5.344082

−12, −30, 10

−14, −28, − 2

(L) Thalamus (61.3% Pulvinar, 2.5% Medial Geniculate Body)

4.7613444

 2

784

0.01593744

0.015419524

4.662963

−2, −6, −6

0, −16, −8

(L) Thalamus (Red Nucleus)

4.5910673

 3

480

0.019446805

5.3822155

12, −30,13

(R) Thalamus (100% Pulvinar)

 4

424

0.016458694

4.751242

16, −28, −2

(R) Thalamus (16.7% Pulvinar)

 5

384

0.015193136

4.555133

20, −22, 68

(R) Precentral Gyrus (BA 4)

 6

336

0.014851548

4.504367

8, −4, −14

(R) Hypothalamus

 7

80

0.010117263

3.6241639

−56, −18, 33

(L) Postcentral Gyrus (BA 2)

 8

80

0.010117263

3.6241639

−36, −34, 45

(L) Inferior Parietal Lobule (BA 40)

 9

64

0.008642835

3.1104991

27, −3, 9

(R) Lentiform Nucleus (Putamen)

 10

64

0.00938297

3.3538606

−38, 4, 12

(L) Insula (BA 13)

Groups with decreased grey matter volumes

 1

208

0.00997

3.9280179

−56, −18, 34

(L) Postcentral Gyrus (BA 2)

 2

96

0.008955

3.6178029

6, 44, 0

(R) Anterior Cingulate (BA 32&24)

 3

96

0.009334

3.8218374

−40, −2, 8

(L) Sub-lobar (Insula)

 4

80

0.009279

3.7407575

0, 33, −26

(L) Medial Frontal Gyrus (BA 11)

 5

80

0.008896

3.611275

−40, 4, 12

(L) Sub-lobar (Insula)

 6

80

0.009279

3.7407575

58, −13, 16

(R) Postcentral Gyrus (BA 43)

 7

56

0.009123

3.6994894

−14, 40, 10

(L) Anterior Cingulate (BA 32)

 8

56

0.009123

3.6994894

−8, −52, 26

(L) Posterior Cingulate (BA 31)

  1. Abbreviations: ALE, activation likelihood estimation; BA, Brodmann area; L, left; R, right